DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12951 and Prss44

DIOPT Version :9

Sequence 1:	NP_649880.1	Gene:	CG12951 / 41110	FlyBaseID:	FBgn0037677	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	NP_683742.2	Gene:	Prss44 / 73336	MGIID:	1920586	Length:	372	Species:	Mus musculus

Alignment Length:	247	Identity:	86/247 - (34%)
Similarity:	126/247 - (51%)	Gaps:	33/247 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 SRVVNGTDSSVLKYPFVVSLRSYDGSHSCGGSIISKHFVMTAAHCTNGRPADTLSIQFGVTNISA 92
            :|:|.|..:...|:|:.|||:.:. .|.||||:|||.:|:|||||..|..  ..::..|..::.:
Mouse   110 ARIVGGRPAPARKWPWQVSLQVHK-QHICGGSLISKWWVITAAHCVYGHL--DYAVFMGDADLWS 171

  Fly    93 MGPNVVGIKKIIQHEDFDPTRQNANDISLLMVEEPFEFDGVSVAPVELPALAFAVPQSDAGVEGV 157
            ..|..:.::.||.|:||...|...:||:|:::..|..: .|::.||.:|..:|.|   ..|....
Mouse   172 KRPVRIPVQDIIVHQDFSMMRTVVHDIALVLLAFPVNY-SVNIQPVCIPEKSFLV---QPGTLCW 232

  Fly   158 LIGWGLNDTYGSVQDTLQEVSLKIYSDEECTS-------------RHNGQTDPKYHICGGVDEGG 209
            :.|||.....|.....|||:.|.|...|:|..             :..|       :||..::||
Mouse   233 VTGWGKVLEQGRSSRILQEIELNIIRHEKCNQILKDIMGNIFTLVQEGG-------VCGYNEKGG 290

  Fly   210 KGQCSGDSGGPLI--YNGQ--QVGIVSWSIKPCTVAPYPGVYCKVSQYVDWI 257
            .. |.|||||||:  :|..  |||||||.: .|....|||||.:||.|.|||
Mouse   291 DA-CQGDSGGPLVCEFNKTWVQVGIVSWGL-GCGRIGYPGVYTEVSYYRDWI 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12951	NP_649880.1	Tryp_SPc	29..257	CDD:214473	84/244 (34%)
CG12951	NP_649880.1	Tryp_SPc	30..260	CDD:238113	85/245 (35%)
Prss44	NP_683742.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	31..72
		Tryp_SPc	111..340	CDD:214473	84/244 (34%)
		Tryp_SPc	112..340	CDD:238113	83/243 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920