DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12951 and ST14

DIOPT Version :9

Sequence 1:	NP_649880.1	Gene:	CG12951 / 41110	FlyBaseID:	FBgn0037677	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	NP_068813.1	Gene:	ST14 / 6768	HGNCID:	11344	Length:	855	Species:	Homo sapiens

Alignment Length:	254	Identity:	80/254 - (31%)
Similarity:	121/254 - (47%)	Gaps:	35/254 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 SRVVNGTDSSVLKYPFVVSLRSYDGSHSCGGSIISKHFVMTAAHCTNGRPADTLSIQFG------ 86
            :|||.|||:...::|:.|||.:....|.||.|:||.:::::||||.    .|....::.
Human   613 ARVVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAAHCY----IDDRGFRYSDPTQWT 673

  Fly    87 -------VTNISAMGPNVVGIKKIIQHEDFDPTRQNANDISLLMVEEPFEFDGVSVAPVELPALA 144
                   .:..||.|.....:|:||.|..|:....: .||:||.:|:|.|:..: |.|:.||..:
Human   674 AFLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFD-YDIALLELEKPAEYSSM-VRPICLPDAS 736

  Fly   145 FAVPQSDAGVEGVLIGWGLNDTYGSVQDTLQEVSLKIYSDEECTSRHNGQTDPKYHICGGVDEGG 209
            ...|   ||....:.|||.....|:....||:..:::.:...|.:....|..|:. :|.|...||
Human   737 HVFP---AGKAIWVTGWGHTQYGGTGALILQKGEIRVINQTTCENLLPQQITPRM-MCVGFLSGG 797

  Fly   210 KGQCSGDSGGPL--------IYNGQQVGIVSWSIKPCTVAPYPGVYCKVSQYVDWIKSN 260
            ...|.|||||||        |:   |.|:|||. ..|.....||||.::..:.||||.|
Human   798 VDSCQGDSGGPLSSVEADGRIF---QAGVVSWG-DGCAQRNKPGVYTRLPLFRDWIKEN 852

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12951	NP_649880.1	Tryp_SPc	29..257	CDD:214473	76/248 (31%)
CG12951	NP_649880.1	Tryp_SPc	30..260	CDD:238113	78/250 (31%)
ST14	NP_068813.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		SEA	88..>171	CDD:307516
		CUB	227..332	CDD:238001
		CUB	340..444	CDD:238001
		LDLa	454..486	CDD:238060
		LDLa	488..523	CDD:238060
		LDLa	525..559	CDD:238060
		LDLa	567..602	CDD:238060
		Tryp_SPc	615..852	CDD:238113	78/250 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920