Protein Alignment CG12951 and PRSS2

DIOPT Version :9

• Sequence 1: NP_649880.1
• Gene: CG12951 / 41110
• FlyBaseID: FBgn0037677
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 266
• Identity: 94/266 - (35%)
• Similarity: 136/266 - (51%)
• Gaps: 28/266 - (10%)

  Fly     9 LSLIVILAVTTVGQAAP--SISRVVNGTDSSVLKYPFVVSLRSYDGSHSCGGSIISKHFVMTAAH 71
            ::|::||.......|||  ...::|.|........|:.|||.|  |.|.||||:||:.:|::|.|
Human     1 MNLLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNS--GYHFCGGSLISEQWVVSAGH 63

  Fly    72 C--------TNGRPAD--TLSIQFGVTNISAMGPN--VVGIKKIIQHEDFDPTRQNANDISLLMV 124
            |        .:||..:  .:.::.|..||..:..|  .:...|||:|..:: :|...|||.|:.:
Human    64 CYKSAINSKLSGRGCEYHRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYN-SRTLDNDILLIKL 127

  Fly   125 EEPFEFDGVSVAPVELPALAFAVPQSDAGVEGVLIGWGLNDTYGS-VQDTLQEVSLKIYSDEECT 188
            ..|...:. .|:.:.||.   |.|.  ||.|.::.|||...:.|: ..|.||.:...:.|..||.
Human   128 SSPAVINS-RVSAISLPT---APPA--AGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECE 186

  Fly   189 SRHNGQ-TDPKYHICGGVDEGGKGQCSGDSGGPLIYNGQQVGIVSWSIKPCTVAPYPGVYCKVSQ 252
            :.:.|: |:..:  |.|..||||..|.||||||::.||:..|||||.. .|.....||||.||..
Human   187 ASYPGKITNNMF--CVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGY-GCAQKNRPGVYTKVYN 248

  Fly   253 YVDWIK 258
            ||||||
Human   249 YVDWIK 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12951	NP_649880.1	Tryp_SPc	29..257	CDD:214473	85/241 (35%)
		Tryp_SPc	30..260	CDD:238113	88/243 (36%)
PRSS2	NP_001290343.1	Tryp_SPc	23..253	CDD:214473	85/241 (35%)
		Tryp_SPc	24..256	CDD:238113	88/243 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8476
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.910