DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12951 and tmprss9

DIOPT Version :9

Sequence 1:	NP_649880.1	Gene:	CG12951 / 41110	FlyBaseID:	FBgn0037677	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	XP_021325244.1	Gene:	tmprss9 / 562051	ZFINID:	ZDB-GENE-050208-573	Length:	788	Species:	Danio rerio

Alignment Length:	244	Identity:	77/244 - (31%)
Similarity:	124/244 - (50%)	Gaps:	21/244 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 SRVVNGTDSSVLKYPFVVSLRSYDGSHSCGGSIISKHFVMTAAHC--TNGRPADTLSIQFGVTNI 90
            :|:|.|.::...::|:.|||| ..|.|:||.||::..::::||||  ....|.|..:: .|...:
Zfish   230 NRIVGGENTRHGEFPWQVSLR-LRGRHTCGASIVNSRWLVSAAHCFEVENNPKDWTAL-VGANQV 292

  Fly    91 SAMGPN--VVGIKKIIQHEDFDPTRQNANDISLLMVEEPFEFDGVSVAPVELPALAFAVPQSDAG 153
            |.....  :|.||.::....:||...: :|:::|.:|.|.:|... |.||.:|:.:...   ..|
Zfish   293 SGAEAEAFIVNIKSLVMSPKYDPMTTD-SDVTVLELETPLKFSHY-VQPVCIPSSSHVF---TPG 352

  Fly   154 VEGVLIGWG-LNDTYGSVQDTLQEVSLKIYSDEEC--TSRHNGQTDPKYHICGGVDEGGKGQCSG 215
            ...::.||| ||.....|..|||:..:||...:.|  :|.:.|...... :|.|..:|....|.|
Zfish   353 QNCIVSGWGALNQYTTEVPSTLQKAIVKIIDSKVCNKSSVYRGALTQNM-MCAGFLQGKVDSCQG 416

  Fly   216 DSGGPL---IYNGQQ--VGIVSWSIKPCTVAPYPGVYCKVSQYVDWIKS 259
            ||||||   :..|:.  .|||||.: .|.....||||.:|::..:||.|
Zfish   417 DSGGPLACEVAAGRYFLAGIVSWGV-GCAQINKPGVYSRVTKLRNWIVS 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12951	NP_649880.1	Tryp_SPc	29..257	CDD:214473	74/239 (31%)
CG12951	NP_649880.1	Tryp_SPc	30..260	CDD:238113	76/242 (31%)
tmprss9	XP_021325244.1	SEA	52..146	CDD:307516
		LDLa	185..220	CDD:238060
		Tryp_SPc	232..462	CDD:238113	73/238 (31%)
		LDLa	510..544	CDD:238060
		Tryp_SPc	557..783	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010