DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12951 and prss60.2

DIOPT Version :9

Sequence 1:	NP_649880.1	Gene:	CG12951 / 41110	FlyBaseID:	FBgn0037677	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	NP_001099071.1	Gene:	prss60.2 / 541408	ZFINID:	ZDB-GENE-050320-109	Length:	328	Species:	Danio rerio

Alignment Length:	271	Identity:	92/271 - (33%)
Similarity:	131/271 - (48%)	Gaps:	31/271 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 SLSLIV-----ILAVTTVGQAAPSISRVVNGTDSSVLKYPFVVSLRS--YDGSHSCGGSIISKHF 65
            :|:|::     :..:...|| ||..||:|.|.::....:|:.|||:|  | |.|.||||:||..:
Zfish     8 TLTLLICVKGSLSQLNVCGQ-APLNSRIVGGVNAPEGSWPWQVSLQSPRY-GGHFCGGSLISSEW 70

  Fly    66 VMTAAHCTNGRPADTLSIQFGVTNISAMGPNV----VGIKKIIQHEDFDPTRQNANDISLLMVEE 126
            |:|||||..|....:|.:..|  ..:..|.|.    ..:.|||.|..:: :..|.|||:||.:..
Zfish    71 VLTAAHCLPGVSESSLVVYLG--RRTQQGVNTHETSRNVAKIIVHSSYN-SNTNDNDIALLRLSS 132

  Fly   127 PFEFDGVSVAPVELPALAFAVPQSDAGVEGVLIGWGLNDTYGSVQ----DTLQEVSLKIYSDEEC 187
            ...|:.. :.||   .||.......||....:.|||  |....|.    ..|||..:.:.:::.|
Zfish   133 AVTFNDY-IRPV---CLAAQNSVYSAGTSSWITGWG--DVQAGVNLPAPGILQETMIPVVANDRC 191

  Fly   188 TSRHNGQTDPKYHICGGVDEGGKGQCSGDSGGPLIYN----GQQVGIVSWSIKPCTVAPYPGVYC 248
            .::....|.....||.|:.:|||..|.||||||::..    ..|.||.||.. .|.....||||.
Zfish   192 NAQLGSGTVTNNMICAGLAKGGKDTCQGDSGGPMVTRLCTVWIQAGITSWGY-GCADPNSPGVYT 255

  Fly   249 KVSQYVDWIKS 259
            :||||..||.|
Zfish   256 RVSQYQSWISS 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12951	NP_649880.1	Tryp_SPc	29..257	CDD:214473	82/241 (34%)
CG12951	NP_649880.1	Tryp_SPc	30..260	CDD:238113	84/244 (34%)
prss60.2	NP_001099071.1	Tryp_SPc	33..264	CDD:214473	82/241 (34%)
		Tryp_SPc	34..267	CDD:238113	84/244 (34%)
		Somatomedin_B	296..326	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920