DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12951 and Prss36

DIOPT Version :9

Sequence 1:	NP_649880.1	Gene:	CG12951 / 41110	FlyBaseID:	FBgn0037677	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	XP_038942639.1	Gene:	Prss36 / 497040	RGDID:	1593186	Length:	874	Species:	Rattus norvegicus

Alignment Length:	270	Identity:	90/270 - (33%)
Similarity:	131/270 - (48%)	Gaps:	49/270 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 GQAAPSISRVVNGTDSSVLKYPFVVSLRSYDGSHSCGGSIISKHFVMTAAHC--TNG--RPADTL 81
            |:..|| ||:|.|:|:....:|:.|||. :.|.|.||||:|:..:|::||||  |||  .|||..
  Rat    51 GRPEPS-SRIVGGSDAHPGTWPWQVSLH-HGGGHICGGSLIAPSWVLSAAHCFVTNGTLEPADEW 113

  Fly    82 SIQFGVTNISAMGP----NVVGIKKIIQHEDFDPTRQNANDISLLMVEEPFEFDGVSVAPVELPA 142
            |:..||.  |..||    ::..:..|:..:::......| |::||.:..|.:. |.||.||.||.
  Rat   114 SVLLGVH--SQDGPLEGAHMRSVATILVPDNYSRVELGA-DLALLRLASPAKL-GPSVKPVCLPR 174

  Fly   143 LA--FAVPQSDAGVEGVLIGWGLNDTYGSVQDT--------LQEVSLKIYSDEECTSRHNG---- 193
            .:  ||     .|......||      |.||::        ||||.||:..:..|...::.
  Rat   175 ASHLFA-----HGTACWATGW------GDVQESDPLPVPWVLQEVELKLLGETACQCLYSRPGPF 228

  Fly   194 ----QTDPKYHICGGVDEGGKGQCSGDSGGPLI-YNGQQ---VGIVSWSIKPCTVAPYPGVYCKV 250
                |..|.. :|.|..||.:..|.|||||||: .:|.:   .||.|:.. .|.....|||:..|
  Rat   229 NLTLQLLPGM-LCAGYPEGRRDTCQGDSGGPLVCEDGGRWFLAGITSFGF-GCGRRNRPGVFTAV 291

  Fly   251 SQYVDWIKSN 260
            :.|..||:.:
  Rat   292 AHYESWIREH 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12951	NP_649880.1	Tryp_SPc	29..257	CDD:214473	84/257 (33%)
CG12951	NP_649880.1	Tryp_SPc	30..260	CDD:238113	85/259 (33%)
Prss36	XP_038942639.1	Tryp_SPc	59..301	CDD:238113	85/259 (33%)
		Tryp_SPc	338..532	CDD:419748
		Tryp_SPc	607..802	CDD:419748
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.110