DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12951 and prss27

DIOPT Version :9

Sequence 1:	NP_649880.1	Gene:	CG12951 / 41110	FlyBaseID:	FBgn0037677	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	XP_031749235.1	Gene:	prss27 / 496619	XenbaseID:	XB-GENE-5744470	Length:	724	Species:	Xenopus tropicalis

Alignment Length:	252	Identity:	87/252 - (34%)
Similarity:	125/252 - (49%)	Gaps:	30/252 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 SRVVNGTDSSVLKYPFVVSLRSYDGSHSCGGSIISKHFVMTAAHC-TNGRPADTLSIQFGVTNIS 91
            ||::.|..:...::|:.||.|: :|.|.|||::|||.:|::|||| .:...|.:::...|...|.
Frog    32 SRIMGGQSAQEGQWPWQVSFRN-NGGHFCGGTLISKQYVISAAHCFPSSSSASSVTAVLGAYMID 95

  Fly    92 AMGPNVVGIKKIIQHEDFDPTRQN---ANDISLLMVEEPFEFDGVSVAPVELPALAFAVPQSDAG 153
            ....|.|.|.  :|.....|:..|   :.||||:.:..|..|... :.||.|||.....|   .|
Frog    96 QPDGNQVAIP--VQSATNYPSYVNEGDSGDISLVQLASPVTFTNY-ILPVCLPADTVTFP---TG 154

  Fly   154 VEGVLIGWG--LNDTYGSVQDTLQEVSLKIYSDEECTSRHNGQTDPKY-------H---ICGGVD 206
            ::..:.|||  .:|.......|||||::.:....||.:.:  ||...|       |   ||.|..
Frog   155 LQCWVTGWGNIASDVSLVSPMTLQEVAVPLIDANECNALY--QTPNSYGTSSISVHSDMICAGFI 217

  Fly   207 EGGKGQCSGDSGGPLI--YNGQ--QVGIVSWSIKPCTVAPYPGVYCKVSQYVDWIKS 259
            .|||..|.|||||||:  .:||  ..|:||:. :.|..|..||||..:..|.|||.|
Frog   218 NGGKDSCQGDSGGPLVCSSSGQWFLAGVVSFG-EGCGQAYRPGVYTLMPSYTDWIVS 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12951	NP_649880.1	Tryp_SPc	29..257	CDD:214473	83/247 (34%)
CG12951	NP_649880.1	Tryp_SPc	30..260	CDD:238113	85/250 (34%)
prss27	XP_031749235.1	Tryp_SPc	34..271	CDD:238113	82/246 (33%)
prss27	XP_031749235.1	Tryp_SPc	420..659	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910