DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12951 and st14

DIOPT Version :9

Sequence 1:	NP_649880.1	Gene:	CG12951 / 41110	FlyBaseID:	FBgn0037677	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	XP_012821897.2	Gene:	st14 / 448647	XenbaseID:	XB-GENE-1008784	Length:	845	Species:	Xenopus tropicalis

Alignment Length:	252	Identity:	77/252 - (30%)
Similarity:	122/252 - (48%)	Gaps:	35/252 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 SRVVNGTDSSVLKYPFVVSLRSYDGSHSCGGSIISKHFVMTAAHCTNGRPADTLSIQFGVTNI-- 90
            ||:|.|.::...::|:.|||......|:||.|::|...:::||||..    |..|:::...::
Frog   603 SRIVGGVNADTGEFPWQVSLHVKGNKHTCGASLVSPTMLISAAHCFQ----DDQSMRYSDASLWT 663

  Fly    91 SAMG---------PNVV--GIKKIIQHEDFDPTRQNANDISLLMVEEPFEFDGVSVAPVELPALA 144
            :.:|         .:||  .||:|:.|..|:....: ||||:|.:|:|.::... :.|:.:|...
Frog   664 AYLGLHDQAQLNSKDVVERKIKRIMAHIGFNDNTYD-NDISVLELEKPVDYTDF-IQPICIPEST 726

  Fly   145 FAVPQSDAGVEGVLIGWGLNDTYGSVQDTLQEVSLKIYSDEECTSRHNGQTDPKYHICGGVDEGG 209
            ...|   .|....:.|||.....|.....||:..::|.:..||....:||..|:. :|.|...||
Frog   727 HDFP---VGKPIWVTGWGALKEGGGAAVILQKAEIRIINQTECNKLLDGQLTPRM-LCAGFVSGG 787

  Fly   210 KGQCSGDSGGPL--------IYNGQQVGIVSWSIKPCTVAPYPGVYCKVSQYVDWIK 258
            ...|.|||||||        :|   ..|||||. :.|.....||||.:|:...|||:
Frog   788 IDACQGDSGGPLSSVELNNKVY---LAGIVSWG-EGCARRNKPGVYTRVAMMRDWIR 840

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12951	NP_649880.1	Tryp_SPc	29..257	CDD:214473	74/248 (30%)
CG12951	NP_649880.1	Tryp_SPc	30..260	CDD:238113	75/250 (30%)
st14	XP_012821897.2	SEA	76..167	CDD:396113
		CUB	216..320	CDD:238001
		CUB	328..432	CDD:238001
		LDLa	442..474	CDD:238060
		LDLa	476..511	CDD:238060
		LDLa	513..547	CDD:238060
		LDLa	554..587	CDD:197566
		Tryp_SPc	604..839	CDD:214473	74/248 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010