Protein Alignment CG12951 and KLK2

DIOPT Version :9

• Sequence 1: NP_649880.1
• Gene: CG12951 / 41110
• FlyBaseID: FBgn0037677
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 92/281 - (32%)
• Similarity: 134/281 - (47%)
• Gaps: 57/281 - (20%)

  Fly     6 DLSLSLIVILAVTTVGQAAPSI-SRVVNGTDSSVLKYPFVVSLRSYDGSHSCGGSIISKHFVMTA 69
            ||.||  :.|:|...| |.|.| ||:|.|.:......|:.|::.|:..:| |||.::...:|:||
Human     3 DLVLS--IALSVGCTG-AVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAH-CGGVLVHPQWVLTA 63

  Fly    70 AHCTN-------GR-----PADT-----LSIQFGVTNISAMGPNVVGIKKIIQHEDFDPTRQNAN 117
            |||..       ||     |.||     :|..|         |:.:....:::|:...|...:::
Human    64 AHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSF---------PHPLYNMSLLKHQSLRPDEDSSH 119

  Fly   118 DISLLMVEEPFEF-DGVSV--APVELPALAFAVPQSDAGVEGVLIGWGLNDTYGSVQD------- 172
            |:.||.:.||.:. |.|.|  .|.:.|||         |......||      ||::.
Human   120 DLMLLRLSEPAKITDVVKVLGLPTQEPAL---------GTTCYASGW------GSIEPEEFLRPR 169

  Fly   173 TLQEVSLKIYSDEECTSRHNGQTDPKYHICGGVDEGGKGQCSGDSGGPLIYNGQQVGIVSWSIKP 237
            :||.|||.:.|::.| :|...:...::.:|.|:..|||..|.|||||||:.||...||.||..:|
Human   170 SLQCVSLHLLSNDMC-ARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEP 233

  Fly   238 CTVAPYPGVYCKVSQYVDWIK 258
            |.:...|.||.||..|..|||
Human   234 CALPEKPAVYTKVVHYRKWIK 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12951	NP_649880.1	Tryp_SPc	29..257	CDD:214473	78/254 (31%)
		Tryp_SPc	30..260	CDD:238113	80/256 (31%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	80/256 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	157	1.000	Inparanoid score	I4287
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8476
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.970