Protein Alignment CG12951 and KLK1

DIOPT Version :9

• Sequence 1: NP_649880.1
• Gene: CG12951 / 41110
• FlyBaseID: FBgn0037677
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_002248.1
• Gene: KLK1 / 3816
• HGNCID: 6357
• Length: 262
• Species: Homo sapiens
• Alignment Length: 264
• Identity: 84/264 - (31%)
• Similarity: 123/264 - (46%)
• Gaps: 26/264 - (9%)

  Fly     9 LSLIVILAVTTVGQAAPSISRVVNGTDSSVLKYPFVVSLRSYDGSHSCGGSIISKHFVMTAAHCT 73
            |.|.:.|::...|.|.|..||:|.|.:......|:..:|..: .:..|||.::.:.:|:|||||.
Human     4 LVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHF-STFQCGGILVHRQWVLTAAHCI 67

  Fly    74 NGRPADTLSIQFGVTNI--SAMGPNVVGIKKIIQHEDF------DPTRQ----NANDISLLMVEE 126
                :|...:..|..|:  .......|.:.:...|..|      :.|||    .::|:.||.:.|
Human    68 ----SDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTE 128

  Fly   127 PFEFDGVSVAPVELPALAFAVPQSDAGVEGVLIGWG-LNDTYGSVQDTLQEVSLKIYSDEECTSR 190
            |.:....:|..||||     ..:.:.|...:..||| :.....|..|.||.|.|||..::||...
Human   129 PADTITDAVKVVELP-----TEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKA 188

  Fly   191 H-NGQTDPKYHICGGVDEGGKGQCSGDSGGPLIYNGQQVGIVSWSIKPCTVAPYPGVYCKVSQYV 254
            | ...||  :.:|.|..||||..|.|||||||:.:|...|:.||...||.....|.|..:|..||
Human   189 HVQKVTD--FMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYV 251

  Fly   255 DWIK 258
            .||:
Human   252 KWIE 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12951	NP_649880.1	Tryp_SPc	29..257	CDD:214473	75/241 (31%)
		Tryp_SPc	30..260	CDD:238113	76/243 (31%)
KLK1	NP_002248.1	Tryp_SPc	25..257	CDD:238113	76/243 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	157	1.000	Inparanoid score	I4287
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8476
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.970