DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12951 and Prss53

DIOPT Version :9

Sequence 1:	NP_649880.1	Gene:	CG12951 / 41110	FlyBaseID:	FBgn0037677	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	NP_001074737.1	Gene:	Prss53 / 330657	MGIID:	2652890	Length:	552	Species:	Mus musculus

Alignment Length:	282	Identity:	69/282 - (24%)
Similarity:	119/282 - (42%)	Gaps:	51/282 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LIVILAVTTV----------GQAAPSISRVVNGTDSSVLKYPFVVSLRSYDGSHSCGGSIISKHF 65
            |:::.||..:          ||..|.......| ::...::|:..|:|. .|.|.|.||:::..:
Mouse     9 LLIVGAVVVIEGLQAAQRACGQRGPGPPEPQEG-NTLPGEWPWQASVRR-QGVHICSGSLVADTW 71

  Fly    66 VMTAAHCTNGRPADTL---SIQFGVTNISAMGPNV--VGIKKIIQHEDFDPTRQNANDISLLMVE 125
            |:|||||........|   |:..|........|..  ||:..:...:.::...| .:|::||.:.
Mouse    72 VLTAAHCFEKMATAELSSWSVVLGSLKQEGQSPGAEEVGVAALQLPKAYNHYSQ-GSDLALLQLT 135

  Fly   126 EPFEFDGVSVAPVELPALAFAVPQSDAGVEGVLIGWGLNDTYGSVQDTLQEVSLKIYSDEECTSR 190
            .|     .....:.||...:..|   .|......||..|.:  .|..||:.:.|::.|...|...
Mouse   136 HP-----TVQTTLCLPQPTYHFP---FGASCWATGWDQNTS--DVSRTLRNLRLRLISRPTCNCL 190

  Fly   191 HNGQTDPKYH------------ICGGVDEGGKGQCSGDSGGPLIY---NGQ--QVGIVSWSIKPC 238
            :|     :.|            :|||...|.:|.|.||||||::.   :|.  ||||:|::.| |
Mouse   191 YN-----RLHQRLLSNPARPGMLCGGAQPGEQGPCQGDSGGPVMCREPDGHWVQVGIISFTSK-C 249

  Fly   239 TVAPYPGVYCKVSQYVDWIKSN 260
            .....|.:...::.:..|::::
Mouse   250 AQEDTPVLLTDMAVHSSWLQAH 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12951	NP_649880.1	Tryp_SPc	29..257	CDD:214473	62/249 (25%)
CG12951	NP_649880.1	Tryp_SPc	30..260	CDD:238113	63/251 (25%)
Prss53	NP_001074737.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..46		4/19 (21%)
		Tryp_SPc	45..271	CDD:238113	62/243 (26%)
		Tryp_SPc	311..522	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.110