DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12951 and Tmprss11e

DIOPT Version :9

Sequence 1:	NP_649880.1	Gene:	CG12951 / 41110	FlyBaseID:	FBgn0037677	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	XP_038948843.1	Gene:	Tmprss11e / 305265	RGDID:	1561698	Length:	444	Species:	Rattus norvegicus

Alignment Length:	243	Identity:	79/243 - (32%)
Similarity:	123/243 - (50%)	Gaps:	24/243 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 RVVNGTDSSVLKYPFVVSLRSYDGSHSCGGSIISKHFVMTAAHC--TNGRPADTLSIQFGVTNIS 91
            |:|.||.:...::|:..||: :||||.||.::||..::::||||  |:..|: ..:..||.|
  Rat   212 RIVGGTSAEEGEWPWQSSLQ-WDGSHRCGATLISNTWLVSAAHCFRTHKDPS-RWTASFGAT--- 271

  Fly    92 AMGPNV-VGIKKIIQHEDFD-PTRQNANDISLLMVEEPFEFDGVSVAPVELPALAFAVPQSDAGV 154
            ...|.: .||::||.||.:: |:..  .||:|:.:..|..... :|..|.||.   |..:...|.
  Rat   272 LQPPKLTTGIRRIIVHEKYNYPSHD--YDIALVELSRPVPCTN-AVHKVCLPD---ANHEFQPGQ 330

  Fly   155 EGVLIGWGLNDTYGSVQDTLQEVSLKIYSDEECT--SRHNGQTDPKYHICGGVDEGGKGQCSGDS 217
            ...:.|:|.....|..|:.|::|.:.....:.|.  ..:||...|:. :|.|..:|.|..|.|||
  Rat   331 RMFVTGFGALRNDGFAQNYLRQVQVDYIDTQTCNRPQSYNGAITPRM-LCAGFLKGEKDACQGDS 394

  Fly   218 GGPLIYNGQQ-----VGIVSWSIKPCTVAPYPGVYCKVSQYVDWIKSN 260
            ||||:....:     .|:|||. ..|.....||||.:|:.:.|||.||
  Rat   395 GGPLVTPDVRDVWYLAGVVSWG-DECGQPNKPGVYTRVTAFRDWITSN 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12951	NP_649880.1	Tryp_SPc	29..257	CDD:214473	75/238 (32%)
CG12951	NP_649880.1	Tryp_SPc	30..260	CDD:238113	76/240 (32%)
Tmprss11e	XP_038948843.1	SEA	71..176	CDD:396113
Tmprss11e	XP_038948843.1	Tryp_SPc	213..441	CDD:238113	76/240 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010