Protein Alignment CG12951 and TPSG1

DIOPT Version :10

• Sequence 1: NP_649880.1
• Gene: CG12951 / 41110
• FlyBaseID: FBgn0037677
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_036599.4
• Gene: TPSG1 / 25823
• HGNCID: 14134
• Length: 321
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 86/282 - (30%)
• Similarity: 126/282 - (44%)
• Gaps: 57/282 - (20%)

  Fly    11 LIVILAVTTV-------GQAAPSIS----RVVNGTDSSVLKYPFVVSLRSYDGSHSCGGSIISKH 64
            |:::|||..|       |...|.:|    |:|.|..:....:|:..||| ....|.||||::|..
Human     8 LLLLLAVPGVSLRTLQPGCGRPQVSDAGGRIVGGHAAPAGAWPWQASLR-LRRVHVCGGSLLSPQ 71

  Fly    65 FVMTAAHCTNGR-PADTLSIQFGVTNISAMGPNVVGIKKIIQHEDFDPTRQ--NANDISLLMVEE 126
            :|:|||||.:|. .:....:..|...|: :.|:...:::||.|.  .|:.|  .:.||:|:.:..
Human    72 WVLTAAHCFSGSLNSSDYQVHLGELEIT-LSPHFSTVRQIILHS--SPSGQPGTSGDIALVELSV 133

  Fly   127 PFEFDGVSVAPVELPALAFAVPQSD---AGVEGVLIGWG-------LNDTYGSVQDTLQEVSLKI 181
            |..... .:.||.||      ..||   .|:...:.|||       |...|     :|:||.:.:
Human   134 PVTLSS-RILPVCLP------EASDDFCPGIRCWVTGWGYTREGEPLPPPY-----SLREVKVSV 186

  Fly   182 YSDEECTSRHNG------QTDPKYHICGGVDEGGKGQCSGDSGGPLI--YNGQ--QVGIVSWSIK 236
            ...|.|...:.|      |.|   .:|.   .|....|..||||||:  .||.  |.|.|||. :
Human   187 VDTETCRRDYPGPGGSILQPD---MLCA---RGPGDACQDDSGGPLVCQVNGAWVQAGTVSWG-E 244

  Fly   237 PCTVAPYPGVYCKVSQYVDWIK 258
            .|.....||||.:|..||:||:
Human   245 GCGRPNRPGVYTRVPAYVNWIR 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12951	NP_649880.1	Tryp_SPc	30..260	CDD:238113	77/252 (31%)
TPSG1	NP_036599.4	Tryp_SPc	38..268	CDD:238113	77/252 (31%)