Protein Alignment CG12951 and KLK5

DIOPT Version :9

• Sequence 1: NP_649880.1
• Gene: CG12951 / 41110
• FlyBaseID: FBgn0037677
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_001070959.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Alignment Length: 269
• Identity: 73/269 - (27%)
• Similarity: 119/269 - (44%)
• Gaps: 41/269 - (15%)

  Fly     3 SNQDLSLSLIVILAVTTVGQAA---PSISRVVNGTDSSVLKYPFVVSLRSYDGSHSCGGSIISKH 64
            |||||...         .|:.|   .|.||::||:|..:...|:..:|........||..::...
Human    46 SNQDLGAG---------AGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQ 101

  Fly    65 FVMTAAHCTNGRPADTLSIQFGVTNISAM---GPNVVGIKKIIQHEDFDPTRQNANDISLLMVE- 125
            :::|||||..    ....::.|..::|.:   |..:....|.|.|..:... .::||:.|:.:.
Human   102 WLLTAAHCRK----KVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHP-GHSNDLMLIKLNR 161

  Fly   126 --EPFEFDGVSVAPVELPALAFAVPQSDAGVEGVLIGWGLNDTYGSVQ----DTLQEVSLKIYSD 184
              .|.:    .|.|:.:.:..     ..||.:.::.|||   |..|.|    ..||.:::.:.|.
Human   162 RIRPTK----DVRPINVSSHC-----PSAGTKCLVSGWG---TTKSPQVHFPKVLQCLNISVLSQ 214

  Fly   185 EECTSRHNGQTDPKYHICGGVDEGGKGQCSGDSGGPLIYNGQQVGIVSWSIKPCTVAPYPGVYCK 249
            :.|...:..|.|... .|.| |:.|:..|.||||||::.||...|:|||...||.....||||..
Human   215 KRCEDAYPRQIDDTM-FCAG-DKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTN 277

  Fly   250 VSQYVDWIK 258
            :.::..||:
Human   278 LCKFTKWIQ 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12951	NP_649880.1	Tryp_SPc	29..257	CDD:214473	62/237 (26%)
		Tryp_SPc	30..260	CDD:238113	63/239 (26%)
KLK5	NP_001070959.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		10/30 (33%)
		Tryp_SPc	66..285	CDD:214473	62/237 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	157	1.000	Inparanoid score	I4287
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8476
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.970