DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12951 and ELANE

DIOPT Version :9

Sequence 1:NP_649880.1 Gene:CG12951 / 41110 FlyBaseID:FBgn0037677 Length:265 Species:Drosophila melanogaster
Sequence 2:NP_001963.1 Gene:ELANE / 1991 HGNCID:3309 Length:267 Species:Homo sapiens


Alignment Length:253 Identity:76/253 - (30%)
Similarity:120/253 - (47%) Gaps:20/253 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 LSLIVILAVTTVGQAAPSISRVVNGTDSSVLKYPFVVSLRSYDGSHSCGGSIISKHFVMTAAHCT 73
            |.|..:|....:|..|.: |.:|.|..:....:||:|||: ..|.|.||.::|:.:|||:||||.
Human    10 LFLACVLPALLLGGTALA-SEIVGGRRARPHAWPFMVSLQ-LRGGHFCGATLIAPNFVMSAAHCV 72

  Fly    74 NGRPADTLSIQFGVTNISAMGP--NVVGIKKIIQHEDFDPTRQNANDISLLMVEEPFEFDGVSVA 136
            .......:.:..|..|:|...|  .|..:::|.:: .:||... .|||.:|.:......: .:|.
Human    73 ANVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFEN-GYDPVNL-LNDIVILQLNGSATIN-ANVQ 134

  Fly   137 PVELPALAFAVPQSDAGVEGVLIGWGLNDTYGSVQDTLQEVSLKIYSDEECTSRHNGQTDPKYHI 201
            ..:|||....:..   ||:.:.:||||......:...|||:::.:.:  ....|.|        :
Human   135 VAQLPAQGRRLGN---GVQCLAMGWGLLGRNRGIASVLQELNVTVVT--SLCRRSN--------V 186

  Fly   202 CGGVDEGGKGQCSGDSGGPLIYNGQQVGIVSWSIKPCTVAPYPGVYCKVSQYVDWIKS 259
            |..|.....|.|.||||.||:.||...||.|:....|....||..:..|:|:|:||.|
Human   187 CTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDS 244

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12951NP_649880.1 Tryp_SPc 29..257 CDD:214473 67/229 (29%)
Tryp_SPc 30..260 CDD:238113 70/232 (30%)
ELANENP_001963.1 Tryp_SPc 30..245 CDD:238113 70/232 (30%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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