DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12951 and St14

DIOPT Version :9

Sequence 1:	NP_649880.1	Gene:	CG12951 / 41110	FlyBaseID:	FBgn0037677	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	XP_036010597.1	Gene:	St14 / 19143	MGIID:	1338881	Length:	875	Species:	Mus musculus

Alignment Length:	247	Identity:	82/247 - (33%)
Similarity:	125/247 - (50%)	Gaps:	21/247 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 SRVVNGTDSSVLKYPFVVSLRSYDGSHSCGGSIISKHFVMTAAHC----TNGRPAD-TLSIQF-G 86
            :|||.||::...::|:.|||.:....|.||.|:||..::::||||    .|.:.:| |:...| |
Mouse   633 ARVVGGTNADEGEWPWQVSLHALGQGHLCGASLISPDWLVSAAHCFQDDKNFKYSDYTMWTAFLG 697

  Fly    87 V---TNISAMGPNVVGIKKIIQHEDFDPTRQNANDISLLMVEEPFEFDGVSVAPVELPALAFAVP 148
            :   :..||.|...:.:|:||.|..|:....: .||:||.:|:..|:..| |.|:.||......|
Mouse   698 LLDQSKRSASGVQELKLKRIITHPSFNDFTFD-YDIALLELEKSVEYSTV-VRPICLPDATHVFP 760

  Fly   149 QSDAGVEGVLIGWGLNDTYGSVQDTLQEVSLKIYSDEECTSRHNGQTDPKYHICGGVDEGGKGQC 213
               ||....:.|||.....|:....||:..:::.:...|......|..|:. :|.|...||...|
Mouse   761 ---AGKAIWVTGWGHTKEGGTGALILQKGEIRVINQTTCEDLMPQQITPRM-MCVGFLSGGVDSC 821

  Fly   214 SGDSGGPLI---YNGQ--QVGIVSWSIKPCTVAPYPGVYCKVSQYVDWIKSN 260
            .|||||||.   .:|:  |.|:|||. :.|.....||||.::....||||.:
Mouse   822 QGDSGGPLSSAEKDGRMFQAGVVSWG-EGCAQRNKPGVYTRLPVVRDWIKEH 872

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12951	NP_649880.1	Tryp_SPc	29..257	CDD:214473	79/241 (33%)
CG12951	NP_649880.1	Tryp_SPc	30..260	CDD:238113	81/243 (33%)
St14	XP_036010597.1	SEA	108..198	CDD:396113
		CUB	247..352	CDD:238001
		CUB	360..464	CDD:238001
		LDLa	474..506	CDD:238060
		LDLa	512..543	CDD:238060
		LDLa	545..579	CDD:238060
		LDLa	587..622	CDD:238060
		Tryp_SPc	635..872	CDD:238113	81/243 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920