Protein Alignment CG12951 and Klk1b4

DIOPT Version :10

• Sequence 1: NP_649880.1
• Gene: CG12951 / 41110
• FlyBaseID: FBgn0037677
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_035045.2
• Gene: Klk1b4 / 18048
• MGIID: 97320
• Length: 256
• Species: Mus musculus
• Alignment Length: 266
• Identity: 83/266 - (31%)
• Similarity: 127/266 - (47%)
• Gaps: 38/266 - (14%)

  Fly    11 LIVILAVTTVG-QAAPSISRVVNGTDSSVLKYPFVVSLRSYDGSHSCGGSIISKHFVMTAAHCTN 74
            ||:.||::..| .|||.:...|:..:|.    |:.|::..:: .:.|||.::.:::|:|||||.|
Mouse     4 LILFLALSLGGIDAAPPVQSQVDCENSQ----PWHVAVYRFN-KYQCGGVLLDRNWVLTAAHCYN 63

  Fly    75 GRPADTLSIQFGVTNISAMGPNVVG--IKKIIQHEDFD----------PTRQNANDISLLMVEEP 127
                |...:..|..|.....|:...  :.|.|.|.||:          |....:||:.||.:.:|
Mouse    64 ----DKYQVWLGKNNFLEDEPSDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKP 124

  Fly   128 FEFDGVSVAPVELPALAFAVPQSDAGVEGVLIGWG----LNDTYGSVQDTLQEVSLKIYSDEECT 188
            .:...| |.|:.||     ..:...|...:..|||    :...|   .|.||.|:||:..:|:|.
Mouse   125 ADITDV-VKPITLP-----TEEPKLGSTCLASGWGSTTPIKFKY---PDDLQCVNLKLLPNEDCD 180

  Fly   189 SRHNGQ-TDPKYHICGGVDEGGKGQCSGDSGGPLIYNGQQVGIVSWSIKPCTVAPYPGVYCKVSQ 252
            ..|..: ||..  :|.|..:||...|..|||||||.:|...||.||..:||.....|.||.|:.:
Mouse   181 KAHEMKVTDAM--LCAGEMDGGSYTCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIK 243

  Fly   253 YVDWIK 258
            :..||:
Mouse   244 FSSWIR 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12951	NP_649880.1	Tryp_SPc	30..260	CDD:238113	75/246 (30%)
Klk1b4	NP_035045.2	Tryp_SPc	13..251	CDD:238113	79/257 (31%)
		Activation peptide homolog	18..24		2/5 (40%)