Protein Alignment CG12951 and CFD

DIOPT Version :9

• Sequence 1: NP_649880.1
• Gene: CG12951 / 41110
• FlyBaseID: FBgn0037677
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_001304264.1
• Gene: CFD / 1675
• HGNCID: 2771
• Length: 260
• Species: Homo sapiens
• Alignment Length: 271
• Identity: 71/271 - (26%)
• Similarity: 125/271 - (46%)
• Gaps: 40/271 - (14%)

  Fly     9 LSLIVILAVTTVGQ-----AAPSISRVVNGTDSSVLKYPFVVSLRSYDGSHSCGGSIISKHFVMT 68
            |:::|:|.....|:     |||...|::.|.::.....|::.|:: .:|:|.|||.::::.:|::
Human     7 LAVLVLLGAAACGEEAWAWAAPPRGRILGGREAEAHARPYMASVQ-LNGAHLCGGVLVAEQWVLS 70

  Fly    69 AAHCTNGRPADTLSIQFGVTNISAMGPN--VVGIKKIIQHEDFDPTRQNANDISLLMVEE----- 126
            ||||........:.:..|..::|...|:  :..:.:.:.|.|..|...: :|:.||.:.|
Human    71 AAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTID-HDLLLLQLSEKATLG 134

  Fly   127 ------PFEFDGVSVAPVELPALAFAVPQSDAGVEGVLIGWGLNDTYGSVQDTLQEVSLKIYSDE 185
                  |::.....|||..|..:|               |||:.:..|...|:||.|.|.:....
Human   135 PAVRPLPWQRVDRDVAPGTLCDVA---------------GWGIVNHAGRRPDSLQHVLLPVLDRA 184

  Fly   186 ECTSR--HNGQTDPKYHICGGVDEGGKGQCSGDSGGPLIYNGQQVGIVSWSIKPCTVAPYPGVYC 248
            .|..|  |:|....:. :|  .:...:..|.|||||||:..|...|:|:...:.|.....||:|.
Human   185 TCNRRTHHDGAITERL-MC--AESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYT 246

  Fly   249 KVSQYVDWIKS 259
            :|:.|..||.|
Human   247 RVASYAAWIDS 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12951	NP_649880.1	Tryp_SPc	29..257	CDD:214473	61/242 (25%)
		Tryp_SPc	30..260	CDD:238113	63/245 (26%)
CFD	NP_001304264.1	Tryp_SPc	32..255	CDD:214473	61/242 (25%)
		Tryp_SPc	33..258	CDD:238113	63/245 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910