DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12951 and St14

DIOPT Version :9

Sequence 1:	NP_649880.1	Gene:	CG12951 / 41110	FlyBaseID:	FBgn0037677	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	NP_446087.1	Gene:	St14 / 114093	RGDID:	69288	Length:	855	Species:	Rattus norvegicus

Alignment Length:	248	Identity:	83/248 - (33%)
Similarity:	124/248 - (50%)	Gaps:	27/248 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 SRVVNGTDSSVLKYPFVVSLRSYDGSHSCGGSIISKHFVMTAAHC----TNGRPAD-TLSIQF-G 86
            :|||.||::...::|:.|||.:....|.||.|:||..::::||||    |..:.:| |:...| |
  Rat   613 ARVVGGTNADEGEWPWQVSLHALGQGHLCGASLISPDWLVSAAHCFQDETIFKYSDHTMWTAFLG 677

  Fly    87 V---TNISAMGPNVVGIKKIIQHEDFDPTRQNANDISLLMVEEPFEFDGVSVAPVELPALAFAVP 148
            :   :..||.|.....:|:||.|..|:....: .||:||.:|:|.|:..| |.|:.||......|
  Rat   678 LLDQSKRSASGVQEHKLKRIITHPSFNDFTFD-YDIALLELEKPAEYSTV-VRPICLPDNTHVFP 740

  Fly   149 QSDAGVEGVLIGWGLNDTYGSVQDTLQEVSLKIYSDEECTSRHNGQTDPKYHICGGVDEGGKGQC 213
               ||....:.|||.....|:....||:..:::.:...|......|..|:. :|.|...||...|
  Rat   741 ---AGKAIWVTGWGHTKEGGTGALILQKGEIRVINQTTCEELLPQQITPRM-MCVGFLSGGVDSC 801

  Fly   214 SGDSGGPL--------IYNGQQVGIVSWSIKPCTVAPYPGVYCKVSQYVDWIK 258
            .|||||||        |:   |.|:|||. :.|.....||||.::.:..||||
  Rat   802 QGDSGGPLSSVEKDGRIF---QAGVVSWG-EGCAQRNKPGVYTRIPEVRDWIK 850

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12951	NP_649880.1	Tryp_SPc	29..257	CDD:214473	80/244 (33%)
CG12951	NP_649880.1	Tryp_SPc	30..260	CDD:238113	82/246 (33%)
St14	NP_446087.1	SEA	88..178	CDD:396113
		CUB	214..332	CDD:238001
		CUB	340..444	CDD:238001
		LDLa	454..486	CDD:238060
		LDLa	492..523	CDD:238060
		LDLa	525..559	CDD:238060
		LDLa	567..602	CDD:238060
		Tryp_SPc	615..852	CDD:238113	82/246 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010