DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12951 and LOC100005420

DIOPT Version :9

Sequence 1:	NP_649880.1	Gene:	CG12951 / 41110	FlyBaseID:	FBgn0037677	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	XP_021332645.1	Gene:	LOC100005420 / 100005420	-ID:	-	Length:	798	Species:	Danio rerio

Alignment Length:	255	Identity:	81/255 - (31%)
Similarity:	128/255 - (50%)	Gaps:	29/255 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 PSISRVVNGTDSSVLKYPFVVSLRSYDGSHSCGGSIISKHFVMTAAHCTNG---RPADTLSIQFG 86
            |..||:|.|.|:...::|:..||: ..|.|.|||:::|..:|::||||.:.   .|: ..::..|
Zfish   559 PFSSRIVGGADAVEGEWPWQASLQ-IRGRHICGGALVSAQWVVSAAHCFHDDRYSPS-VWTVYLG 621

  Fly    87 VTNISAMGPN--VVGIKKIIQHEDFDPTRQNANDISLLMVEEPFEFDGVSVAPVELPALAFAVPQ 149
            ...:|:.|.:  .||:..|..|..:|....: .|::||.:..|. :.|....||       .||.
Zfish   622 KLRLSSSGQSEEAVGVSLIHLHHYYDDETHD-YDVALLRLARPV-WAGTLAQPV-------CVPP 677

  Fly   150 SDAGVEGVLI----GWGLNDTYGSVQDTLQEVSLKIYSDEECTSRHNGQTDPKYHICGGVDEGGK 210
            ....:|..|:    |||.....|:|.|.||:|.:::.|::.|...:.....|:. ||.|...|||
Zfish   678 VTHQLEPELLCWVTGWGALREGGAVSDVLQKVDVRLVSEDACVRSYGYLISPRM-ICAGYRSGGK 741

  Fly   211 GQCSGDSGGPLIYNGQQ-----VGIVSWSIKPCTVAPYPGVYCKVSQYVDWIKSNQIISA 265
            ..|.|||||||:.....     .|:|||. :.|..|.|.|||.::::...|||  ::||:
Zfish   742 DACQGDSGGPLVCQEPSGRWFLAGVVSWG-RGCGRADYYGVYTRITKLSVWIK--RMISS 798

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12951	NP_649880.1	Tryp_SPc	29..257	CDD:214473	74/241 (31%)
CG12951	NP_649880.1	Tryp_SPc	30..260	CDD:238113	76/243 (31%)
LOC100005420	XP_021332645.1	SEA	76..169	CDD:307516
		LDLa	446..476	CDD:238060
		LDLa	481..512	CDD:238060
		LDLa	518..553	CDD:238060
		Tryp_SPc	564..794	CDD:238113	76/244 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010