Protein Alignment HP1e and hpl-2

DIOPT Version :10

• Sequence 1: NP_649878.1
• Gene: HP1e / 41108
• FlyBaseID: FBgn0037675
• Length: 174
• Species: Drosophila melanogaster
• Sequence 2: NP_001022654.1
• Gene: hpl-2 / 176506
• WormBaseID: WBGene00001996
• Length: 303
• Species: Caenorhabditis elegans
• Alignment Length: 164
• Identity: 37/164 - (22%)
• Similarity: 70/164 - (42%)
• Gaps: 53/164 - (32%)

  Fly    15 SENSTDFEETEE-----YIVERILDRR-HYMGQLQYLVKWLDYSDEDNTWESAADLDCHSLIDSI 73
            |..||...:.|:     ::||::||:| ...|:.::|::|..:.:.|::||...:|.|..::|..
 Worm     2 SSKSTKRAKIEDPKDNVFMVEKVLDKRTGKAGRDEFLIQWQGFPESDSSWEPRENLQCVEMLDEF 66

  Fly    74 ESQ----------------------------KSLKRGQELNNQYETKAKRLKIDPCLVVDSPFNH 110
            |.:                            |..|:....|:::..:.|:||   |:|
 Worm    67 EREFSKREKPIRKRHSQKPEPSEDQADPEEDKDEKKETNQNDKFSLEGKQLK---CIV------- 121

  Fly   111 GFTAQEILKGAKNNGEISFLIRFWHLDQPQVVPS 144
            |.|        |..||:.||.:|.. |..:::|:
 Worm   122 GLT--------KGPGELHFLCKFSD-DTARLLPA 146

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HP1e	NP_649878.1	CD_CSD	27..71	CDD:349274	13/44 (30%)
		CSD_HP1e_insect	111..163	CDD:349337	10/34 (29%)
hpl-2	NP_001022654.1	CD_HP1_like	18..68	CDD:349316	14/49 (29%)
		CD_CSD	109..>153	CDD:475127	15/57 (26%)