DRSC/TRiP Functional Genomics Resources

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Protein Alignment sage and ATOH8

DIOPT Version :9

Sequence 1:NP_524287.1 Gene:sage / 41105 FlyBaseID:FBgn0037672 Length:268 Species:Drosophila melanogaster
Sequence 2:XP_011531441.1 Gene:ATOH8 / 84913 HGNCID:24126 Length:328 Species:Homo sapiens


Alignment Length:256 Identity:72/256 - (28%)
Similarity:95/256 - (37%) Gaps:61/256 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 TDQLLSSTAGVPGDPPPVLVPVSATTGGPYLSGGSE--GEAESSEQPVLLELGAPQSSSCPAVSL 64
            |:.|...|..:...|.||.|||......| ..||::  ||...|.        ||:.|.  |...
Human    57 TNGLRDRTHRLQPVPVPVPVPVPVAPAVP-PRGGTDTAGERGGSR--------APEVSD--ARKR 110

  Fly    65 NYTLTADGAGLLAYAPTHPHSYSPSVMGGYEKEAHNMGLLPPTYSVIPQPVSMWHAGQVATGSPV 129
            .:.|.|.|.||....|..|.:......||.|.:......|.|...:...|.....:...|..:| 
Human   111 CFALGAVGPGLPTPPPPPPPAPQSQAPGGPEAQPFREPGLRPRILLCAPPARPAPSAPPAPPAP- 174

  Fly   130 GLECNKPSELVPP-----PMYMSYS---------------------GGSIANSTEVDIAKEHNPA 168
                  |...|.|     |...|||                     |.:.|.|:|:         
Human   175 ------PESTVRPAPPTRPGESSYSSISHVIYNNHQDSSASPRKRPGEATAASSEI--------- 224

  Fly   169 WREKALQMEKDYRRTACDRERTRMRDMNRAFDLLRSKLPISKPNGKKYSKIESLRIAINYI 229
               ||||..:  |..|..|||||:..::.||:.||.::|... .|:|.||:..||||.|||
Human   225 ---KALQQTR--RLLANARERTRVHTISAAFEALRKQVPCYS-YGQKLSKLAILRIACNYI 279

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sageNP_524287.1 HLH 181..233 CDD:278439 23/49 (47%)
ATOH8XP_011531441.1 HLH 231..282 CDD:278439 23/52 (44%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3898
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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