DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment sage and neurod6

DIOPT Version :9

Sequence 1:NP_524287.1 Gene:sage / 41105 FlyBaseID:FBgn0037672 Length:268 Species:Drosophila melanogaster
Sequence 2:NP_001072273.1 Gene:neurod6 / 779726 XenbaseID:XB-GENE-969227 Length:337 Species:Xenopus tropicalis


Alignment Length:109 Identity:37/109 - (33%)
Similarity:48/109 - (44%) Gaps:23/109 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   150 GGSIANSTEVDIAKEHNPAWREK--------------------ALQMEKDYRRTACDRERTRMRD 194
            |..|..|.|.:..:|.....||:                    .::..|..|..|..|||.||..
 Frog    45 GKHIKRSPEEETEQEEEDEDREEEDENGLPRRRGPRKKKMTKVRIERIKVRRVEANARERGRMHG 109

  Fly   195 MNRAFDLLRSKLP-ISKPNGKKYSKIESLRIAINYINHLQAMLR 237
            :|.|.|.||..:| .||.  :|.||||:||:|.|||..|..:||
 Frog   110 LNDALDNLRKVVPCYSKT--QKLSKIETLRLAKNYIWALSEILR 151

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sageNP_524287.1 HLH 181..233 CDD:278439 26/52 (50%)
neurod6NP_001072273.1 bHLH_TS_NeuroD4_ATOH3 74..151 CDD:381564 28/78 (36%)
Neuro_bHLH 153..272 CDD:372170
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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