Protein Alignment sage and Bhlhe22

DIOPT Version :10

• Sequence 1: NP_524287.1
• Gene: sage / 41105
• FlyBaseID: FBgn0037672
• Length: 268
• Species: Drosophila melanogaster
• Sequence 2: NP_067535.3
• Gene: Bhlhe22 / 59058
• MGIID: 1930001
• Length: 355
• Species: Mus musculus
• Alignment Length: 279
• Identity: 71/279 - (25%)
• Similarity: 94/279 - (33%)
• Gaps: 102/279 - (36%)

  Fly     5 LLSSTAGVPGDPPPVLVPVSAT---TGGPYLSGGSEGEAESSEQ----------PVLLELGAPQS 56
            ||..:|||.|:|....:|..|.   ..|.....||..|:...||          .::|..|.|..
Mouse    97 LLVGSAGVGGEPSLSSLPAGAALCLKYGESAGRGSVAESSGGEQSPDDDSDGRCELVLRAGGPDP 161

  Fly    57 SSCPAVSLNYTLTADGAGLLAYAPTHPHSYSPSVMGGYEKEA--------HNMGLLPPTYSVIPQ 113
            .:.|           |||                 ||..|.|        |....|||
Mouse   162 RASP-----------GAG-----------------GGSAKVAEGCSNAHLHGGSGLPP------- 191

  Fly   114 PVSMWHAGQVATGSPVGLECNKPSELVPPPMYMSYSGGSIANSTEVDIAKEHNPAWREKALQMEK 178
                  .|..:.|...|                 ..|||...|.|            :|||::..
Mouse   192 ------GGPTSGGGSGG-----------------GGGGSSKKSKE------------QKALRLNI 221

  Fly   179 DYRRTACDRERTRMRDMNRAFDLLRSKLPIS-KPNGKKYSKIESLRIAINYI----NHLQAMLRE 238
            :      .|||.||.|:|.|.|.||:.:|.: .|:.:|.|||.:|.:|.|||    ..|:.|.|.
Mouse   222 N------ARERRRMHDLNDALDELRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALEEMRRL 280

  Fly   239 SSVGQNGNGCCAWSGGSSS 257
            .:....|....|.|..||:
Mouse   281 VAYLNQGQAISAASLPSSA 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sage	NP_524287.1	bHLH_TS	181..236	CDD:381396	23/59 (39%)
Bhlhe22	NP_067535.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	34..90
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	128..215		28/156 (18%)
		bHLH_TS_bHLHe22_bHLHb5	217..286	CDD:381524	26/74 (35%)