Protein Alignment sage and hand2

DIOPT Version :10

• Sequence 1: NP_524287.1
• Gene: sage / 41105
• FlyBaseID: FBgn0037672
• Length: 268
• Species: Drosophila melanogaster
• Sequence 2: NP_571701.3
• Gene: hand2 / 58150
• ZFINID: ZDB-GENE-000511-1
• Length: 205
• Species: Danio rerio
• Alignment Length: 222
• Identity: 54/222 - (24%)
• Similarity: 84/222 - (37%)
• Gaps: 70/222 - (31%)

  Fly    80 PTHP----HSYS-PSVMGGYEKEAHNMGLL-------PPTYSVIPQPVSMWHAGQVATGSPVGLE 132
            |.||    ..|| .:....:|:..:..|.|       ||.|::.|.     ::.:.:||:| ||:
Zfish     8 PHHPVMHHDGYSFAAASRCHEEPPYFHGWLISHPEMSPPDYTMAPS-----YSPEYSTGAP-GLD 66

  Fly   133 CNKPSELVPPPMYMSYSGGSIANSTEVDIAKEHNPAWREKALQMEKDYRRTACDRERTRMRDMNR 197
                        :..|.|...|.:..:      .|...::        |.||..:||.|.:.:|.
Zfish    67 ------------HSHYGGVPGAGAVGM------GPRTVKR--------RPTANRKERRRTQSINS 105

  Fly   198 AFDLLRSKLPISKPNGKKYSKIESLRIAINYINHLQAMLRESSVGQNG----------------- 245
            ||..||..:| :.|...|.|||::||:|.:||.:|..:|.:..  |||
Zfish   106 AFAELRECIP-NVPADTKLSKIKTLRLATSYIAYLMDILDKDE--QNGETEAFKAEFKKTDAKEE 167

  Fly   246 ------NGCCAWSGGSSSPYDNGNDHW 266
                  |.....||.|:.....|...|
Zfish   168 RRKKEMNDVLKSSGSSNDKKTKGRTGW 194

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sage	NP_524287.1	bHLH_TS	181..236	CDD:381396	23/54 (43%)
hand2	NP_571701.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	76..103		8/40 (20%)
		bHLH_TS_HAND2	88..149	CDD:381477	24/71 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	158..194		5/35 (14%)