Protein Alignment sage and MESP1

DIOPT Version :9

• Sequence 1: NP_524287.1
• Gene: sage / 41105
• FlyBaseID: FBgn0037672
• Length: 268
• Species: Drosophila melanogaster
• Sequence 2: NP_061140.1
• Gene: MESP1 / 55897
• HGNCID: 29658
• Length: 268
• Species: Homo sapiens
• Alignment Length: 208
• Identity: 58/208 - (27%)
• Similarity: 85/208 - (40%)
• Gaps: 61/208 - (29%)

  Fly    59 CPAVSLNYTLTADGAGLLAYAPTHPHSYSPSVMGGYEKEAHNMGLLPPT-----YSVIPQPVSMW 118
            ||.:|.::.|:|      |:.||.    .|                ||:     .|::..|.| |
Human     6 CPPLSESWMLSA------AWGPTR----RP----------------PPSDKDCGRSLVSSPDS-W 43

  Fly   119 HAGQVATGSPVGLECNKPSELVPPPMYMSYSGGSIANSTEVDIAKEHNPAWREKALQMEKDYRRT 183
              |.....|||.... :|..|..|........|:                   ::.::....|::
Human    44 --GSTPADSPVASPA-RPGTLRDPRAPSVGRRGA-------------------RSSRLGSGQRQS 86

  Fly   184 ACDRERTRMRDMNRAFDLLRSKLPIS-KPNGKKYSKIESLRIAINYINHLQAM--LRESSVGQNG 245
            |.:||:.|||.:.||...||..||.| .|.|:..:|||:||:||.||.||.|:  |.|.|:.:.
Human    87 ASEREKLRMRTLARALHELRRFLPPSVAPAGQSLTKIETLRLAIRYIGHLSAVLGLSEESLQRR- 150

  Fly   246 NGCCAWSGGSSSP 258
               |...|.:.||
Human   151 ---CRQRGDAGSP 160

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sage	NP_524287.1	HLH	181..233	CDD:278439	26/52 (50%)
MESP1	NP_061140.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	17..93		23/124 (19%)
		bHLH_TS_Mesp	83..147	CDD:381508	30/63 (48%)
		CPLCP	163..167
		2 X 2 AA tandem repeats of G-Q	182..185

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149877
Domainoid	1	1.000	49	1.000	Domainoid score	I11802
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5450
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	5	4.830