DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment sage and NEUROG3

DIOPT Version :9

Sequence 1:NP_524287.1 Gene:sage / 41105 FlyBaseID:FBgn0037672 Length:268 Species:Drosophila melanogaster
Sequence 2:NP_066279.2 Gene:NEUROG3 / 50674 HGNCID:13806 Length:214 Species:Homo sapiens


Alignment Length:131 Identity:42/131 - (32%)
Similarity:59/131 - (45%) Gaps:37/131 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   150 GGSIANSTEVDIAKEHNPAWREKALQMEKDYRRTACDRERTRMRDMNRAFDLLRSKLPISKPNGK 214
            ||.....:|:.::|:            .:..|:.|.||||.||.::|.|.|.||..|| :.|:..
Human    66 GGRSRPKSELALSKQ------------RRSRRKKANDRERNRMHNLNSALDALRGVLP-TFPDDA 117

  Fly   215 KYSKIESLRIAINYINHLQAMLRESS------------VGQNGNGCCAWSGGSSSPYDNGNDHWG 267
            |.:|||:||.|.|||..|...||.:.            .|:.|:     .||  ||.|     ||
Human   118 KLTKIETLRFAHNYIWALTQTLRIADHSLYALEPPAPHCGELGS-----PGG--SPGD-----WG 170

  Fly   268 A 268
            :
Human   171 S 171

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sageNP_524287.1 HLH 181..233 CDD:278439 26/51 (51%)
NEUROG3NP_066279.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..98 12/43 (28%)
HLH 81..140 CDD:238036 27/59 (46%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3898
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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