Protein Alignment sage and Atoh8

DIOPT Version :10

• Sequence 1: NP_524287.1
• Gene: sage / 41105
• FlyBaseID: FBgn0037672
• Length: 268
• Species: Drosophila melanogaster
• Sequence 2: NP_001102711.1
• Gene: Atoh8 / 500200
• RGDID: 1561512
• Length: 322
• Species: Rattus norvegicus
• Alignment Length: 256
• Identity: 71/256 - (27%)
• Similarity: 94/256 - (36%)
• Gaps: 65/256 - (25%)

  Fly     7 SSTAGVPG-----DPPPVLVPVSATTGGPYLSGGSEGEAESSEQPVLLELGAPQSSSCPAVSLNY 66
            |:||...|     .|.|:..||.|:.......||....|..     ...:.||:.|.  |....:
  Rat    57 SATAATNGLRDRTQPFPIATPVPASVAPAVPPGGGTDTARE-----FRGIRAPEVSD--ARKRGF 114

  Fly    67 TLTADGAGLLAYAPTHP-----HSYSPSVMGGYEKEAHNMGLLPPTYSVIPQPVSMWHAGQVATG 126
            .|...|.||    ||.|     .|.:|   |..|.:......|.|...:...|.....:..:|
  Rat   115 ALGTVGPGL----PTPPPPPASQSLAP---GDPEVQPLREQALRPRILLCAPPARPTPSAPLA-- 170

  Fly   127 SPVGLECNKPSELVPP--PMYMSYS---------------------GGSIANSTEVDIAKEHNPA 168
             |..:....|....||  |...|||                     |.:.|.|||:
  Rat   171 -PPAVPQESPVRPAPPTRPGESSYSSISHVIYNNHPDSSASPRKRPGEATAASTEI--------- 225

  Fly   169 WREKALQMEKDYRRTACDRERTRMRDMNRAFDLLRSKLPISKPNGKKYSKIESLRIAINYI 229
               ||||..:  |..|..|||||:..::.||:.||.::|... .|:|.||:..||||.|||
  Rat   226 ---KALQQTR--RLLANARERTRVHTISAAFEALRKQVPCYS-YGQKLSKLAILRIACNYI 280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sage	NP_524287.1	bHLH_TS	181..236	CDD:381396	23/49 (47%)
Atoh8	NP_001102711.1	PRK12323	<50..>185	CDD:481241	33/144 (23%)
		bHLH_TS_ATOH8	225..292	CDD:381427	27/71 (38%)