DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sage and myf6

DIOPT Version :9

Sequence 1:	NP_524287.1	Gene:	sage / 41105	FlyBaseID:	FBgn0037672	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	NP_001003982.1	Gene:	myf6 / 404208	ZFINID:	ZDB-GENE-040309-2	Length:	239	Species:	Danio rerio

Alignment Length:	173	Identity:	47/173 - (27%)
Similarity:	68/173 - (39%)	Gaps:	38/173 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 PTYSVIPQPVSMWHAGQVATGSPVGLECNKPSELVPPPMYMSYSGGSIANSTEVDIAKEHNPAWR 170
            |.|.....|:|   .||....|..|.|.:....::.||...::..|...             .|.
Zfish    32 PLYEGNDSPLS---PGQDPVPSETGCESSGEEHVLAPPGLQAHCEGQCL-------------MWA 80

  Fly   171 EKALQMEK---DYRRTACDRERTRMRDMNRAFDLLRSKLPISKPNGKKYSKIESLRIAINYINHL 232
            .|..:.:.   |.|:.|..|||.|::.:|.|||.|:.| .:..|| ::..|:|.||.|||||..|
Zfish    81 CKICKRKSAPTDRRKAATLRERRRLKKINEAFDALKKK-TVPNPN-QRLPKVEILRSAINYIEKL 143

  Fly   233 QAMLRESSVGQNGNGCCAWSGGSSSPY-----DN----GNDHW 266
            |.:|......:..|        .:.||     :|    ...||
Zfish   144 QDLLHSLDEQEQSN--------DTDPYTYNLKENHVTPSEYHW 178

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sage	NP_524287.1	HLH	181..233	CDD:278439	23/51 (45%)
myf6	NP_001003982.1	Basic	2..92	CDD:279868	14/75 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	28..59		9/29 (31%)
		HLH	93..144	CDD:278439	23/52 (44%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	182..239
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	50	1.000	Inparanoid score	I5464
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.960