Protein Alignment sage and hlh-8

DIOPT Version :10

• Sequence 1: NP_524287.1
• Gene: sage / 41105
• FlyBaseID: FBgn0037672
• Length: 268
• Species: Drosophila melanogaster
• Sequence 2: NP_509367.1
• Gene: hlh-8 / 181069
• WormBaseID: WBGene00001953
• Length: 178
• Species: Caenorhabditis elegans
• Alignment Length: 181
• Identity: 37/181 - (20%)
• Similarity: 57/181 - (31%)
• Gaps: 64/181 - (35%)

  Fly    89 ETEMLQKKL---------IDYEERLKLVDSGEYEPSPTKSRVFPTGIRKAKGMTETMVNAPIEFA 144
            :|||:::..         :.|..|.: ||..:..|.|...|......|:....|....|..:...
 Worm     4 KTEMMERDAMATVAPYAPVTYHRRAR-VDLDDRLPKPYMPRALQAPDREHPYGTPGHKNYGLSVL 67

  Fly   145 QRVKSAFSADN-----------------------------VNSTQNGTTGAPKTGQSTFFTTRKS 180
            |:..|.|..|:                             :|.|.:..| .|....|.||
 Worm    68 QQHVSFFDIDDNGIIYPWETYSGLRMLGFNIIGSLIIAAVINLTLSYAT-LPGWLPSPFF----- 126

  Fly   181 ADTDEVESNAVHKNRGAKRNSST-------LPPNLSL-------TSPDPLS 217
                .:..:.:||::... :|.|       :|.||.|       |.||.||
 Worm   127 ----PIYIHNIHKSKHGS-DSKTYDNEGRFMPVNLELIFSKYAKTLPDKLS 172

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sage	NP_524287.1	bHLH_TS	181..236	CDD:381396	13/51 (25%)
hlh-8	NP_509367.1	bHLH_TS_TWIST	21..79	CDD:381470	14/58 (24%)