DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment sage and Mesp2

DIOPT Version :9

Sequence 1:NP_524287.1 Gene:sage / 41105 FlyBaseID:FBgn0037672 Length:268 Species:Drosophila melanogaster
Sequence 2:NP_032615.2 Gene:Mesp2 / 17293 MGIID:1096325 Length:370 Species:Mus musculus


Alignment Length:91 Identity:37/91 - (40%)
Similarity:49/91 - (53%) Gaps:15/91 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   181 RRTACDRERTRMRDMNRAFDLLRSKLPIS-KPNGKKYSKIESLRIAINYINHLQAML-------- 236
            |::|.:||:.|||.:.||...||..||.| .|.|:..:|||:||:||.||.||.|:|        
Mouse    81 RQSASEREKLRMRTLARALQELRRFLPPSVAPAGQSLTKIETLRLAIRYIGHLSALLGLSEDSLR 145

  Fly   237 ---RESSVGQNGNGC--CAWSGGSSS 257
               |.|:.....:.|  |. .|||.|
Mouse   146 RRRRRSADAAFSHRCPQCP-DGGSPS 170

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sageNP_524287.1 HLH 181..233 CDD:278439 26/52 (50%)
Mesp2NP_032615.2 HLH 80..133 CDD:278439 25/51 (49%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167839922
Domainoid 1 1.000 50 1.000 Domainoid score I11580
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R5450
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
54.830

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