Protein Alignment sage and OLIG2

DIOPT Version :10

• Sequence 1: NP_524287.1
• Gene: sage / 41105
• FlyBaseID: FBgn0037672
• Length: 268
• Species: Drosophila melanogaster
• Sequence 2: NP_005797.1
• Gene: OLIG2 / 10215
• HGNCID: 9398
• Length: 323
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 68/276 - (24%)
• Similarity: 100/276 - (36%)
• Gaps: 93/276 - (33%)

  Fly     5 LLSSTAGVPGDPPPVLVPV-SATTGGPYLSGGSEGEAESSEQPVLLELGAPQSSSCPAVSLNYTL 68
            |:||....| :|..:.:|. |..:.|...:||:    .||..|          |.||.     .|
Human     7 LVSSRPSSP-EPDDLFLPARSKGSSGSAFTGGT----VSSSTP----------SDCPP-----EL 51

  Fly    69 TADGAGLLAYAPTHPHSYSPSVMGGYEKEAHNMGLLPPTYSVIPQPVSMWHAGQVATGSPVGLEC 133
            :|:..|.:..|..||                                     |....||  |.:.
Human    52 SAELRGAMGSAGAHP-------------------------------------GDKLGGS--GFKS 77

  Fly   134 NKPSELVPPPMYMSYSGGSIANSTEVDIAKEHNPAWREKALQMEKDYRRTACDRERTRMRDMNRA 198
            :..|.       .|.:..:.|:||:.|..:...|..::..|::.        .|||.||.|:|.|
Human    78 SSSST-------SSSTSSAAASSTKKDKKQMTEPELQQLRLKIN--------SRERKRMHDLNIA 127

  Fly   199 FDLLRSKLPISK-PNGKKYSKIESLRIAINYI----NHLQAMLRESS-------VGQNGNGCCAW 251
            .|.||..:|.:. |:.:|.|||.:|.:|.|||    |.|:.|.|..|       .|.:.:.|
Human   128 MDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTNSLEEMKRLVSEIYGGHHAGFHPSAC--- 189

  Fly   252 SGG--SSSPYDNGNDH 265
             ||  .|:|......|
Human   190 -GGLAHSAPLPAATAH 204

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sage	NP_524287.1	bHLH_TS	181..236	CDD:381396	24/59 (41%)
OLIG2	NP_005797.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..107		33/165 (20%)
		bHLH_TS_OLIG2	95..179	CDD:381510	30/91 (33%)