Protein Alignment ATP6AP2 and Atp6ap2

DIOPT Version :9

• Sequence 1: NP_649876.1
• Gene: ATP6AP2 / 41104
• FlyBaseID: FBgn0037671
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_081715.1
• Gene: Atp6ap2 / 70495
• MGIID: 1917745
• Length: 350
• Species: Mus musculus
• Alignment Length: 357
• Identity: 98/357 - (27%)
• Similarity: 165/357 - (46%)
• Gaps: 46/357 - (12%)

  Fly     2 LRVFVIFSLFIAAINASGEFTVLNRPKAISFK-GNDALESHYVGDVLYASMGNAVSGDTNWNGLT 65
            :.|.|:...|:.|.....||::|..|.::.|: ||..:....:.||...|||.:|..|.:|.||.
Mouse     1 MAVLVVLLFFLVAGALGNEFSILRSPGSVVFRNGNWPIPGDRIPDVAALSMGFSVKEDLSWPGLA 65

  Fly    66 INDPFNLAKGVILVHVQGIGHVT-TAGNVKTYELTGS---GTDASLNAL----------AAELEA 116
            :.:.|:..:..|:|.|:|:..:. .||:|.:|.|..:   ..|:..|::          ..:|..
Mouse    66 VGNLFHRPRATIMVMVKGVDKLALPAGSVISYPLENAVPFSLDSVANSIHSLFSEETPVVLQLAP 130

  Fly   117 ANEPVCDIN-----FEQFDDGVQAWKS-CFGDFEAPAAKPTKHLNPS-----LHTADKQFLQEVG 170
            :.|.|..:.     ||.....::..:: .|.:.....:.|...|:.:     |..::.|.|.::.
Mouse   131 SEERVYMVGKANSVFEDLSVTLRQLRNRLFQENSLLNSLPLNSLSRNNEVDLLFLSELQVLHDIS 195

  Fly   171 FINSAADHLAEMAKPSNVLMLRVSVDGVAKAHGEKSVAVEEANKLLSAAISRLLAASQKSSDS-- 233
            .:.|...|||:...|....:....:|.:.|.:||.|....:|:|:|..|:       ||.:|.
Mouse   196 SLLSRHKHLAKDHSPDLYSLELAGLDELGKRYGEDSEQFRDASKILVDAL-------QKFADDMY 253

  Fly   234 --------VLFVQTTEKDVAASRAKRDTIAA---STTNPYNLAVYYGSDYPVIFNIILWFMVVFG 287
                    |..|.....|.:..|..|..:.|   :|.:|||||..|..:|.|:||::||.|:...
Mouse   254 SLYGGNAVVELVTVKSFDTSLVRKSRTILEAKQENTQSPYNLAYKYNLEYSVVFNLVLWIMIGLA 318

  Fly   288 LSLLAICYAIAAMDPGRDSIIYRMTSTRIKKD 319
            |:::...|.|..||||.||||||||:.:|:.|
Mouse   319 LAVIITSYNIWNMDPGYDSIIYRMTNQKIRID 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATP6AP2	NP_649876.1	Renin_r	231..319	CDD:369555	37/100 (37%)
Atp6ap2	NP_081715.1	Renin_r	255..350	CDD:369555	36/94 (38%)
		Mediates retrograde transport to the ER. /evidence=ECO:0000250|UniProtKB:O75787	346..350		1/3 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834821
Domainoid	1	1.000	71	1.000	Domainoid score	I9463
eggNOG	1	0.900	-	-		E1_KOG4737
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H38097
Inparanoid	1	1.050	120	1.000	Inparanoid score	I4767
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48564
OrthoDB	1	1.010	-	-		D1179410at2759
OrthoFinder	1	1.000	-	-		FOG0007261
OrthoInspector	1	1.000	-	-		oto93325
orthoMCL	1	0.900	-	-		OOG6_106424
Panther	1	1.100	-	-	LDO	PTHR13351
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4406
SonicParanoid	1	1.000	-	-		X6151
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.800