Protein Alignment ATP6AP2 and vha-20

DIOPT Version :10

• Sequence 1: NP_649876.1
• Gene: ATP6AP2 / 41104
• FlyBaseID: FBgn0037671
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_510360.1
• Gene: vha-20 / 181526
• WormBaseID: WBGene00010993
• Length: 324
• Species: Caenorhabditis elegans
• Alignment Length: 379
• Identity: 92/379 - (24%)
• Similarity: 153/379 - (40%)
• Gaps: 121/379 - (31%)

  Fly     5 FVIFSLFIAAINASGEFTVLNRPKAISFKGNDALESHYVGDVLYASMGNAVSG--DTNWNGLTIN 67
            ||:....:.|..|:....::..|.::.|...||.    :...|.:::...:.|  ....:|.:::
 Worm     3 FVLLVSALVAACAASSLEIIAAPASLKFPDADAT----LKTTLISTLNENILGLSARQVDGFSVS 63

  Fly    68 -DPFNLAKGVILVHVQGIGHVTTAGNVKTY---------------------------ELTGSGTD 104
             |.|:..:.:.:|.|.|..::...|  |||                           :::..|..
 Worm    64 VDMFSRPRALAVVTVIGADNLNLGG--KTYSTKSDGVENVGFDQDMALIFGADRENVQVSAGGIT 126

  Fly   105 ASLNALAAELEAANEPVCDINFEQFDDGVQAWKSCFGDFEAPAAKPTKHLNPSLHTADKQFLQEV 169
            .|:.||||:.||.:..|                                    :.|.....::|:
 Worm   127 GSMLALAAQQEAVDATV------------------------------------IKTKRSTLVKEL 155

  Fly   170 GFINSAADHLAEMAKPSNVLM------LRVSVDGVA----KAHGEKSVA-VEEANKLLSAAIS-- 221
                .|...||...|.:.|.|      .|||:.|:.    .|..|::|| |:.|.:.|:|:|:
 Worm   156 ----EAVYQLAAAIKSAGVQMDNNADVFRVSITGLVGITESAQKEEAVADVKAAIEALTASINNA 216

  Fly   222 -------RLLA------ASQKSSDSVLFVQTTEKDVAASR-AKRDTIAASTTNPYNLA------- 265
                   .|||      |::||::|        :::.... .||||   .:..|..||
 Worm   217 YGGQAVIELLAFEAESGAAEKSTES--------REIPNHNIQKRDT---KSKTPTQLARENLQVT 270

  Fly   266 VYYGSDYPVIFNIILWFMVVFGLSLLAICYAIAAMDPGRDSIIYRMTSTRIKKD 319
            |...||||.||.|.|..:|:..::|:.|...:|::||.:||||||||:||:|||
 Worm   271 VPVSSDYPAIFAIFLGLVVILVVALIYIVVGMASIDPEKDSIIYRMTTTRMKKD 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATP6AP2	NP_649876.1	Renin_r	231..319	CDD:462287	34/95 (36%)
vha-20	NP_510360.1	Renin_r	216..324	CDD:462287	40/118 (34%)