DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG16736 and UCP3

DIOPT Version :9

Sequence 1:NP_649873.1 Gene:CG16736 / 41101 FlyBaseID:FBgn0037668 Length:277 Species:Drosophila melanogaster
Sequence 2:NP_003347.1 Gene:UCP3 / 7352 HGNCID:12519 Length:312 Species:Homo sapiens


Alignment Length:289 Identity:65/289 - (22%)
Similarity:113/289 - (39%) Gaps:48/289 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 AQLLSHPMELVRVNMQ----------ANVIHHSRLSINHMFRLMARHGLPGFYYGIVAACLRCTV 67
            |.|::.|::..:|.:|          |.::.: |..:..:..::...|....|.|:||...|   
Human    27 ADLVTFPLDTAKVRLQIQGENQAVQTARLVQY-RGVLGTILTMVRTEGPCSPYNGLVAGLQR--- 87

  Fly    68 HTMSTYTLFYNLQDNKYVLMLQPY------NTSMVLGI-----TGFWGGVLATPFAKLAVIRQAD 121
             .||    |.:::...|..:.|.|      |:|:...|     ||......|.|...:.|..||.
Human    88 -QMS----FASIRIGLYDSVKQVYTPKGADNSSLTTRILAGCTTGAMAVTCAQPTDVVKVRFQAS 147

  Fly   122 LTRG-SYERRNYRNFWRGLKCMYAKGGFTYLFTGWK-------INSISSTAVAVLYTPISDKVHT 178
            :..| |...|.|.......:.:..:.|...|   ||       .|:|.:.|..|.|..:.:|:..
Human   148 IHLGPSRSDRKYSGTMDAYRTIAREEGVRGL---WKGTLPNIMRNAIVNCAEVVTYDILKEKLLD 209

  Fly   179 VISWFHRLDEPWLSDLITMALTGSIITVIMTPVDALATLTLNESSHYGRTSYPY-LYRKIIRKHG 242
                :|.|.:.:....::....|...||:.:|||.:.|..:|  |..|:...|. ...|::.:.|
Human   210 ----YHLLTDNFPCHFVSAFGAGFCATVVASPVDVVKTRYMN--SPPGQYFSPLDCMIKMVAQEG 268

  Fly   243 YKGFFFGWKPALMALIPHTVLATFVYRFL 271
            ...|:.|:.|:.:.|....|:....|..|
Human   269 PTAFYKGFTPSFLRLGSWNVVMFVTYEQL 297

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG16736NP_649873.1 Mito_carr 6..81 CDD:278578 16/77 (21%)
Mito_carr 187..277 CDD:278578 20/86 (23%)
UCP3NP_003347.1 Mito_carr 10..110 CDD:278578 19/91 (21%)
Solcar 1 11..105 17/86 (20%)
PTZ00169 14..302 CDD:240302 65/289 (22%)
Mito_carr 112..210 CDD:278578 24/104 (23%)
Solcar 2 114..206 22/94 (23%)
Mito_carr 214..303 CDD:278578 20/86 (23%)
Solcar 3 215..300 20/85 (24%)
Purine nucleotide binding. /evidence=ECO:0000250 279..301 4/19 (21%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0759
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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