DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG16736 and Tpc1

DIOPT Version :9

Sequence 1:	NP_649873.1	Gene:	CG16736 / 41101	FlyBaseID:	FBgn0037668	Length:	277	Species:	Drosophila melanogaster
Sequence 2:	NP_650034.1	Gene:	Tpc1 / 41316	FlyBaseID:	FBgn0037852	Length:	332	Species:	Drosophila melanogaster

Alignment Length:	247	Identity:	56/247 - (22%)
Similarity:	86/247 - (34%)	Gaps:	54/247 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 HHSRLSINHMFRLMARHGLPGFYYGIVAACLRCTVHTMSTYTLFYNLQDNKYVLMLQPYNTSMVL 97
            |.:|..::.|        |.|   |:.||..|.|...:....:.:.||       ::|      |
  Fly    23 HSTREQLHQM--------LAG---GLSAAITRSTCQPLDVLKIRFQLQ-------VEP------L 63

  Fly    98 GITGFWGGVLATPFAKLAVIRQADLTRGSYERRNYRNFWRG------LKCMYAKGGFTYLFTGWK 156
            |......|..|.. :|...|.||  .:..|.......||:|      |..||....|      |.
  Fly    64 GKNAAKEGPGALT-SKYTSIGQA--VKTIYREEGMLAFWKGHNPAQVLSIMYGICQF------WT 119

  Fly   157 INSISSTAVAVLYTPISDKVHTVISWFHRLDEPWLSDLITMALTGSIITVIMTPVDALATLTLNE 221
            ...:|..|....|  ::|..|             ||:.:..|..|....:|.||:|.:.|..:.:
  Fly   120 YEQLSLMAKQTSY--LADHQH-------------LSNFLCGAAAGGAAVIISTPLDVIRTRLIAQ 169

  Fly   222 SSHYGRTSYPYLYRKIIRKHGYKGFFFGWKPALMALIPHTVLATFVYRFLLD 273
            .:..|..:.......|:|:.|.:|.:.|...||:.:.|........||...|
  Fly   170 DTSKGYRNATRAVSAIVRQEGPRGMYRGLSSALLQITPLMGTNFMAYRLFSD 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16736	NP_649873.1	Mito_carr	6..81	CDD:278578	11/47 (23%)
CG16736	NP_649873.1	Mito_carr	187..277	CDD:278578	21/87 (24%)
Tpc1	NP_650034.1	Mito_carr	29..123	CDD:278578	28/126 (22%)
		PTZ00169	33..329	CDD:240302	53/229 (23%)
		Mito_carr	153..222	CDD:278578	17/69 (25%)
		Mito_carr	233..328	CDD:278578
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45441579
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930