Protein Alignment ARSB and CG18278

DIOPT Version :10

• Sequence 1: NP_000037.2
• Gene: ARSB / 411
• HGNCID: 714
• Length: 533
• Species: Homo sapiens
• Sequence 2: NP_725289.1
• Gene: CG18278 / 36487
• FlyBaseID: FBgn0033836
• Length: 492
• Species: Drosophila melanogaster
• Alignment Length: 504
• Identity: 115/504 - (22%)
• Similarity: 186/504 - (36%)
• Gaps: 137/504 - (27%)

Human    22 VVLPLLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGVLLDNYY 86
            :.|..|::|:||..|:.| :.:.|:::.:|:||   .||...|.......::.|..||.|..|.|
  Fly     2 ISLAPLIILVLACLGNTA-SEKLPNILLILSDD---QDVELRGMFPMEHTIEMLGFGGALFHNAY 62

Human    87 T-QPLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPSCV------PLDEKLLPQLLKEAGYTTHMVG 144
            | .|:|.|:|:.||||.|....|.::..:   ...|.      .|:.:.||.:|::.||.|...|
  Fly    63 TPSPICCPARTSLLTGMYAHNHGTRNNSV---SGGCYGPHWRRALEPRALPYILQQHGYNTFFGG 124

Human   145 K-----WHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVAT 204
            |     |..|       ...:|::.::| |.|:..||::              .|....|.   .
  Fly   125 KYLNQYWGAG-------DVPKGWNHFYG-LHGNSRYYNY--------------TLRENSGN---V 164

Human   205 GYKNMYSTNIFTKRAIALITN-HPPEKPLFLYLALQSVHEPL-QVPE--------EYLKPYDFIQ 259
            .|::.|.|::...||...:.| ....:|.|..:|..:.|||. ..|.        |.|:...|.|
  Fly   165 HYESTYLTDLLRDRAADFLRNATQSSEPFFAMVAPPAAHEPFTPAPRHEGVFSHIEALRTPSFNQ 229

Human   260 DKNRHHYAGMVS-----------------------LMDEAVGNVTAALKSSGLWNNTVFIFSTDN 301
            .|...|:....:                       .:||.|..:...|..:....||..|:::||
  Fly   230 VKQDKHWLVRAARRLPNETINTIDTYFQKRWETLLAVDELVVTLMGVLNDTQSLENTYIIYTSDN 294

Human   302 GGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHTN 366
            |..                        ||..|.|..|::..:..  |::    |.|:   ||  .
  Fly   295 GYH------------------------VGQFAQPFDKRQPYETD--INV----PLLI---RG--P 324

Human   367 GTKPLDGFDVWKTISEGSPSPRIELLHNID-PNFVDSSP-----CPRNSMAPAKDDSSLPEYSAF 425
            |..|....|.  .:|....:|.|....:|| |:::|...     ..:....|..:.|.|.||
  Fly   325 GIAPESHIDT--AVSLVDLAPTILAWADIDTPSYMDGQSFHELLLNKRRRVPFFERSLLIEY--- 384

Human   426 NTSVHAAIRHGNWKLLTGYPGCGYWFPPPSQYNVSE-IPSSDPPTKTLW 473
                     .|...|.|..|.|    |.|.:..::: .|::|...:..|
  Fly   385 ---------WGEGTLATFNPEC----PWPEKDRLAQCTPAADCHCQDAW 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ARSB	NP_000037.2	4-S	45..488	CDD:293753	108/481 (22%)
CG18278	NP_725289.1	G6S	24..467	CDD:293766	108/481 (22%)