DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment St2 and ST2A

DIOPT Version :9

Sequence 1:	NP_001287244.1	Gene:	St2 / 41098	FlyBaseID:	FBgn0037665	Length:	316	Species:	Drosophila melanogaster
Sequence 2:	NP_568177.1	Gene:	ST2A / 830592	AraportID:	AT5G07010	Length:	359	Species:	Arabidopsis thaliana

Alignment Length:	285	Identity:	78/285 - (27%)
Similarity:	132/285 - (46%)	Gaps:	44/285 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 QDDVWMVSYPRTGSTWAQEMVW--LLGHQLDYVAAEQDLRLRSPLIELSALFSIDHHETV----- 111
            ::||.:.:.|::|:||.:.:.:  |..|:.|.||:..:          ..||:.:.|:.|
plant    91 ENDVVLATIPKSGTTWLKALTFTILNRHRFDPVASSTN----------HPLFTSNPHDLVPFFEY 145

  Fly   112 -AQKFGNTVDLVRNLPRPRFARSHLPWPLLPEQFETVKPRIVYTARNPKDLCVSYYHYFKLLHGM 175
             ....|:..|| ..|..||...:|||:..|.|..|....::||..|||.|..:|.:||...:...
plant   146 KLYANGDVPDL-SGLASPRTFATHLPFGSLKETIEKPGVKVVYLCRNPFDTFISSWHYTNNIKSE 209

  Fly   176 NGD---FEQFVDLFLEGHTPMGSYWRHVLPFWKRS--QDDNVLFIKYEDMVKDLPSVVRRCARFL 235
            :..   .:|..||:..|....|.:|.|:|.:|:.|  :.:.|.|::|||:..|:.:.::|.|.||
plant   210 SVSPVLLDQAFDLYCRGVIGFGPFWEHMLGYWRESLKRPEKVFFLRYEDLKDDIETNLKRLATFL 274

  Fly   236 -----------GVQSLLDVSTLQKLCDHLTFDKMRANKAVNLEKLLPESSSKFI-RNGKIGDWRN 288
                       ||     |..:.:||......|:..||:   .|.:....::|: |.|::.||.|
plant   275 ELPFTEEEERKGV-----VKAIAELCSFENLKKLEVNKS---NKSIKNFENRFLFRKGEVSDWVN 331

  Fly   289 HMGNEMSERFDEWTERHMRGSGLNF 313
            ::.....||.....:..:.||||.|
plant   332 YLSPSQVERLSALVDDKLGGSGLTF 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
St2	NP_001287244.1	Sulfotransfer_1	55..310	CDD:279075	74/279 (27%)
ST2A	NP_568177.1	Sulfotransfer_1	30..354	CDD:304426	75/281 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	119	1.000	Domainoid score	I1897
eggNOG	1	0.900	-	-		E1_KOG1584
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H101388
Inparanoid	1	1.050	119	1.000	Inparanoid score	I1987
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D780670at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm948
orthoMCL	1	0.900	-	-		OOG6_100094
Panther	1	1.100	-	-	O	PTHR11783
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X38
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.830