DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment St2 and SULT1C3

DIOPT Version :9

Sequence 1:	NP_001287244.1	Gene:	St2 / 41098	FlyBaseID:	FBgn0037665	Length:	316	Species:	Drosophila melanogaster
Sequence 2:	XP_016859642.1	Gene:	SULT1C3 / 442038	HGNCID:	33543	Length:	349	Species:	Homo sapiens

Alignment Length:	283	Identity:	84/283 - (29%)
Similarity:	138/283 - (48%)	Gaps:	27/283 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 ELGESIRSLPVYQDDVWMVSYPRTGSTWAQEMVWLLGHQLDYVAAEQDLRLRSPLIELSALFSID 106
            |..|.:.:.....||:.:.:||::|:||..|:       ||.:..:.|:.      :.....::|
Human    79 EWWEKVCNFQAKPDDLILATYPKSGTTWMHEI-------LDMILNDGDVE------KCKRAQTLD 130

  Fly   107 HHETVAQKFGN----TVDLVRNLPRPRFARSHLPWPLLPEQFETVKPRIVYTARNPKDLCVSYYH 167
            .|..:..||.:    .::.|..:..|:..::|||..|:|........:|||.||||||..|||||
Human   131 RHAFLELKFPHKEKPDLEFVLEMSSPQLIKTHLPSHLIPPSIWKENCKIVYVARNPKDCLVSYYH 195

  Fly   168 YFKLLHGMNG--DFEQFVDLFLEGHTPMGSYWRHVLPFWKRSQDDNVLFIKYEDMVKDLPSVVRR 230
            :.::...|..  :.|:|.:.|:.|....||::.||..:|.......:|::.|||:.|:....:.:
Human   196 FHRMASFMPDPQNLEEFYEKFMSGKVVGGSWFDHVKGWWAAKDMHRILYLFYEDIKKNPKHEIHK 260

  Fly   231 CARFLGVQSLLDVSTLQKLCDHLTFDKMRANKAVNLEKLLP-----ESSSKFIRNGKIGDWRNHM 290
            ...||  :.......:.|:..|.:||.|:.|...| ...:|     .|.|||:|.|..|||:||.
Human   261 VLEFL--EKTWSGDVINKIVHHTSFDVMKDNPMAN-HTAVPAHIFNHSISKFMRKGMPGDWKNHF 322

  Fly   291 GNEMSERFDEWTERHMRGSGLNF 313
            ...::|.||:..|:.|.||.|||
Human   323 TVALNENFDKHYEKKMAGSTLNF 345

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
St2	NP_001287244.1	Sulfotransfer_1	55..310	CDD:279075	78/265 (29%)
SULT1C3	XP_016859642.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1584
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49491
OrthoDB	1	1.010	-	-		D481448at33208
OrthoFinder	1	1.000	-	-		FOG0000045
OrthoInspector	1	1.000	-	-		mtm8578
orthoMCL	1	0.900	-	-		OOG6_100094
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X38
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.730