DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment St2 and sult1st3

DIOPT Version :9

Sequence 1:	NP_001287244.1	Gene:	St2 / 41098	FlyBaseID:	FBgn0037665	Length:	316	Species:	Drosophila melanogaster
Sequence 2:	NP_899191.2	Gene:	sult1st3 / 368270	ZFINID:	ZDB-GENE-030804-28	Length:	301	Species:	Danio rerio

Alignment Length:	277	Identity:	91/277 - (32%)
Similarity:	147/277 - (53%)	Gaps:	21/277 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 ESIRSLPVYQDDVWMVSYPRTGSTWAQEMVWLL--GHQLDYVAAEQDLRLRSPLIELSALFSIDH 107
            |.:::.....||:.:.:||:.|:||...::.||  |::.......|.:.:|.|.:|  |.|.
Zfish    34 EKVKNFQARPDDILIATYPKAGTTWVSYILDLLYFGNESPERQTSQPIYMRVPFLE--ACFE--- 93

  Fly   108 HETVAQKFGNTVDLVRNLP-RPRFARSHLPWPLLPEQFETVKPRIVYTARNPKDLCVSYYHYFKL 171
                ...||  .:|..||| .||..::|||..|:|:.|.....::||.|||.||..|||:|:.::
Zfish    94 ----GIPFG--TELADNLPTSPRLIKTHLPVQLVPKSFWEQNSKVVYVARNAKDNAVSYFHFDRM 152

  Fly   172 LHGM--NGDFEQFVDLFLEGHTPMGSYWRHVLPFWKRSQD-DNVLFIKYEDMVKDLPSVVRRCAR 233
            ..|.  .||:..|:..|:||....|.::.||..:||:.|. .|:|::.|||||:|....|.|...
Zfish   153 NMGQPEPGDWNTFLQKFMEGRNVFGPWYDHVNGYWKKKQTYSNILYMFYEDMVEDTGREVERLCS 217

  Fly   234 FLGVQSLLDVSTLQKLCDHLTFDKMRANKAVNLEKL--LPESSSKFIRNGKIGDWRNHMGNEMSE 296
            |||:.:  ..:..:::...:.||.|:.||..|...:  :....|.|:|.||:||||||.....:|
Zfish   218 FLGLST--SAAERERITKGVQFDAMKQNKMTNYSTIPVMDFKISPFMRKGKVGDWRNHFTVAQNE 280

  Fly   297 RFDEWTERHMRGSGLNF 313
            :|||..::.|:.:.:.|
Zfish   281 QFDEVYKQKMKNTTVKF 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
St2	NP_001287244.1	Sulfotransfer_1	55..310	CDD:279075	89/262 (34%)
sult1st3	NP_899191.2	Sulfotransfer_1	43..294	CDD:279075	89/263 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	144	1.000	Domainoid score	I4547
eggNOG	1	0.900	-	-		E1_KOG1584
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49491
OrthoDB	1	1.010	-	-		D481448at33208
OrthoFinder	1	1.000	-	-		FOG0000045
OrthoInspector	1	1.000	-	-		mtm6392
orthoMCL	1	0.900	-	-		OOG6_100094
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5451
SonicParanoid	1	1.000	-	-		X38
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.760