DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment St2 and Sult2a6

DIOPT Version :9

Sequence 1:	NP_001287244.1	Gene:	St2 / 41098	FlyBaseID:	FBgn0037665	Length:	316	Species:	Drosophila melanogaster
Sequence 2:	NP_036827.3	Gene:	Sult2a6 / 24902	RGDID:	3727	Length:	284	Species:	Rattus norvegicus

Alignment Length:	284	Identity:	84/284 - (29%)
Similarity:	139/284 - (48%)	Gaps:	32/284 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 FIIPRKYVELGESIRSLPVYQDDVWMVSYPRTGSTWAQEMVWLLGHQLD--YVAAEQDLRL--RS 94
            |.||::  .|........|.::|:.:::||::|:.|..|:|.|:..:.|  ::   |.:.:  ||
  Rat    15 FGIPKE--TLQNVCNKFVVKEEDLILLTYPKSGTNWLIEIVCLIQTKGDPKWI---QSVTIWDRS 74

  Fly    95 PLIELSALFSIDHHETVAQKFGNTVDLVRNLPRPRFARSHLPWPLLPEQFETVKPRIVYTARNPK 159
            |.||...     .::.:.:|.|           ||...||||..|..:...:.|.:::|..|||:
  Rat    75 PWIETDL-----GYDMLIKKKG-----------PRLITSHLPMHLFSKSLFSSKAKVIYLIRNPR 123

  Fly   160 DLCVS-YYHYFKLLHGMNGD-FEQFVDLFLEGHTPMGSYWRHVLPFWKRSQDDNVLFIKYEDMVK 222
            |:.|| ||.:.|.......| ...:|:.||:|:.|.||::.|:..:....:.||.|.:.||||.|
  Rat   124 DVLVSGYYFWGKTTLAKKPDSLGTYVEWFLKGYVPYGSWFEHIRAWLSMRELDNFLLLYYEDMKK 188

  Fly   223 DLPSVVRRCARFLGVQSLLDVSTLQKLCDHLTFDKMRANKAVN---LEKLLPESSSKFIRNGKIG 284
            |....:::...|||.:  |:...|..:..:.:|..|:.|...|   :||.|......|:|||..|
  Rat   189 DTMGTIKKICDFLGKK--LEPDELDLVLKYSSFQVMKENNMSNYNLMEKELILPGFTFMRNGTTG 251

  Fly   285 DWRNHMGNEMSERFDEWTERHMRG 308
            ||:||.....:|.||:..:..|.|
  Rat   252 DWKNHFTVAQAEAFDKVFQEKMAG 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
St2	NP_001287244.1	Sulfotransfer_1	55..310	CDD:279075	79/263 (30%)
Sult2a6	NP_036827.3	Sulfotransfer_1	33..277	CDD:279075	79/264 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1584
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D481448at33208
OrthoFinder	1	1.000	-	-		FOG0000045
OrthoInspector	1	1.000	-	-		mtm9151
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X38
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.820