Protein Alignment pum and pum2

DIOPT Version :9

• Sequence 1: NP_001262403.1
• Gene: pum / 41094
• FlyBaseID: FBgn0003165
• Length: 1533
• Species: Drosophila melanogaster
• Sequence 2: NP_001096040.1
• Gene: pum2 / 567494
• ZFINID: ZDB-GENE-081031-76
• Length: 1106
• Species: Danio rerio
• Alignment Length: 1259
• Identity: 441/1259 - (35%)
• Similarity: 564/1259 - (44%)
• Gaps: 397/1259 - (31%)

  Fly   292 HMSSYAQSGGSMYDHHG-------------GAMHP--GMNGGMPKQQPLGPPGAGGPQD-----Y 336
            |.:...::|| :..|.|             |.:||  ||....|..|||   .:|..||     |
Zfish    24 HTNGAPETGG-VRVHAGCPLATVGGARQVPGGVHPLQGMANPNPCTQPL---LSGRSQDDATVGY 84

  Fly   337 VY-------MGGQT----TVPMGAA-----MMPPQNQYMNSSAVAAANRNAAITTSTAKKLWEK- 384
            .:       |||.|    ..|.|..     :........|..|:|..:|... ....||||||.
Zfish    85 FFQRQPGEQMGGCTGNKHRWPTGDGNHVDQLRSVDEMNYNFQALALESRGMG-ELLPAKKLWESD 148

  Fly   385 ---SDGKGVSSSTPGGPLHPLQIPGIGDPSSVWKDHTWSTQGENILVP-----PPSRAYAHGGAS 441
               .||:....              :|:.   |:::.||:....:..|     .|.:.|  .|..
Zfish   149 ELAKDGRKAML--------------VGEE---WRENAWSSSHHALSQPIMVQKRPGQGY--NGTG 194

  Fly   442 DTSNSGNAGILSPRD---STCAKVVEYVFSGSPTNKDSSLSGLEPHLRNLKFDDNDKSRDDKEKA 503
            :||:     :||||.   .....:||||.|.||.:|      ::...||..:.:.|...|.:||.
Zfish   195 ETSS-----VLSPRSEGGGLGVSMVEYVLSSSPGDK------MDGRYRNGGYGEADADPDGREKG 248

  Fly   504 -----NSPFDTN-------GLKKDDQVTNSNGVVNGIDDD-KGFNRTPGSRQPSPAEESQPRPPN 555
                 :|||:.|       |.:.|....|:.|::||:|.| |.||.||||||.||.|..:...|:
Zfish   249 ESKEKSSPFEENKSPEMKVGDEGDTSKANARGLLNGMDRDCKDFNPTPGSRQASPTEAVERLGPS 313

  Fly   556 LLFPPLPFNHMLMDHGQGMGGGLGGVVGSGNGVGGGSGGGGAGGAYAAHQQMAAQMSQLQPPMMN 620
            .....:...|                                      ||.      .||.|
Zfish   314 QAGLEIMVQH--------------------------------------HQH------TLQAP--- 331

  Fly   621 GVGGGMPMAAQSPMLNHQAAGPNHMESPGNLLQQQNFDVQQLFRSQNPGLAAVATNAAAAAAAAA 685
                 .|:..:.|..:.|:....:|   |.:.||...:..|.....|
Zfish   332 -----NPVTNKPPPEDFQSQEAQNM---GGMEQQAGLEALQFDYGGN------------------ 370

  Fly   686 AATSAASAAAAVGAPPVPNGSLQQSQQQQQQQQQQQQQQQMHMAAASQQFLAAQQQAQNAAYAAQ 750
             .....|:.||||.      ....||||..|:......||::.|...|..|||.||.......|.
Zfish   371 -QIQLDSSGAAVGL------FNYDSQQQLFQRSSHLTVQQLNAAQQQQYALAAAQQQHLGLAPAF 428

  Fly   751 QATSYVIN---PGQEAAPYMGMIAAAQM--------PYYGVAPWGMYPGNLIPQQGT-------- 796
            ....|:||   ||.:.....|:.|||.:        .|||| |||:||.||..||.|
Zfish   429 VPNPYIINAAPPGADPYTAAGLAAAATLAGPAVVPPQYYGV-PWGVYPANLFQQQATAAASHSAN 492

  Fly   797 ----------------QPRRPLTPSQQGAENQP------------------YQVI--PAFLDHTG 825
                            ..:|||||.|.....|.                  |||:  .|:.|.||
Zfish   493 QQASSQGPGQQVIRAGSNQRPLTPGQSQQSQQESLAAAATNPTLAFPGMSGYQVLAPAAYYDQTG 557

  Fly   826 SLLMG-GPRTGT--PMRLVSPAPVLVPPGATRA--------------GPP-------PPQGPQLY 866
            :|:|| |.|||.  |:|||. .|:|:.|.|.:|              ||.       ..|.||
Zfish   558 ALVMGPGTRTGLGGPVRLVQ-TPLLINPAAAQAAAAASVSGSGNSMSGPANGLYRSMACQQPQ-- 619

  Fly   867 QPQPQTAQQNLYSQQNGSSVGGLALNTSSLTGRRDSFDRSTSAFS-------PST-MDYTSS--- 920
            |||||        ||......||..|:...:|......:|:|.||       ||| :.::|:
Zfish   620 QPQPQ--------QQLPPPSSGLPSNSFYGSGSVAPSSQSSSLFSHTSAAPPPSTSLGFSSTSGS 676

  Fly   921 ---GVAAAANAVNSTVAQAAAAAAAAAAA---------RGKWPGAMSGAASGAYGALGAGNASAS 973
               |:.:|..|..|:|:.:..::|....:         || ..|:::......|.:||. ::|.|
Zfish   677 LGVGLGSALGAFGSSVSSSTNSSAVRRDSLLASSELYKRG-GGGSLTPIGQSFYNSLGY-SSSPS 739

  Fly   974 PLG-----APITPPP-------SAQSCLLG----------SRAPGAESRQRQQQQQQLAAVGLPA 1016
            |:|     :|:||||       |:.|..||          |.|||||::.|.
Zfish   740 PIGLTPGHSPLTPPPSLPSSHGSSSSIHLGGLPNGSGRYISAAPGAEAKYRS------------- 791

  Fly  1017 TAAAAQAAVAAAANNMFGSNSSIFSNPLAIPGTAAVAAAAAAAAAANSRQVAATAAAAAAVAAAA 1081
                     :.:.:::|.|:|.:|..|.|....:.|..:
Zfish   792 ---------SGSTSSLFSSSSQLFPPPRARYSRSDVMPS-------------------------- 821

  Fly  1082 GGVGGAPQPGRSRLLEDFRNQRYPNLQLRDLANHIVEFSQDQHGSRFIQQKLERATAAEKQMVFS 1146
                     |||||||||||.|:||||||||..|:|||||||||||||||||||||:||:||||.
Zfish   822 ---------GRSRLLEDFRNNRFPNLQLRDLPGHMVEFSQDQHGSRFIQQKLERATSAERQMVFG 877

  Fly  1147 EILAAAYSLMTDVFGNYVIQKFFEFGTPEQKNTLGMQVKGHVLQLALQMYGCRVIQKALESISPE 1211
            |||.|||.||||||||||||||||||:.:||..|..:::||||.|||||||||||||||||||.:
Zfish   878 EILQAAYQLMTDVFGNYVIQKFFEFGSADQKLALATRIRGHVLPLALQMYGCRVIQKALESISSD 942

  Fly  1212 QQ--QEIVHELDGHVLKCVKDQNGNHVVQKCIECVDPVALQFIINAFKGQVYSLSTHPYGCRVIQ 1274
            ||  .:||.|||||||||||||||||||:||||||.|.||||||:||:|||:.||||||||||||
Zfish   943 QQVISDIVRELDGHVLKCVKDQNGNHVVRKCIECVQPQALQFIIDAFQGQVFVLSTHPYGCRVIQ 1007

  Fly  1275 RILEHCTAEQTTPILDELHEHTEQ------------------------LIQDQYGNYVIQHVLEH 1315
            |||||||.|||.|||:|||:|:||                        |.:||||||||||||||
Zfish  1008 RILEHCTQEQTLPILEELHQHSEQLGQKYQGVSLEMTPKTYYTVSSDALFKDQYGNYVIQHVLEH 1072

  Fly  1316 GKQEDKSILINSVRGKVLVLSQHK 1339
            |:.||||.::..||||||.|||||
Zfish  1073 GRPEDKSKIVAEVRGKVLALSQHK 1096

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pum	NP_001262403.1	Pumilio	1106..1424	CDD:153420	188/260 (72%)
pum2	NP_001096040.1	Pumilio	837..>1096	CDD:153420	186/258 (72%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582071
Domainoid	1	1.000	133	1.000	Domainoid score	I5025
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	617	1.000	Inparanoid score	I864
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000719
OrthoInspector	1	1.000	-	-		otm26492
orthoMCL	1	0.900	-	-		OOG6_100436
Panther	1	1.100	-	-	LDO	PTHR12537
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1032
SonicParanoid	1	1.000	-	-		X849
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	10.010