Protein Alignment pum and Pum2

DIOPT Version :9

• Sequence 1: NP_001262403.1
• Gene: pum / 41094
• FlyBaseID: FBgn0003165
• Length: 1533
• Species: Drosophila melanogaster
• Sequence 2: XP_038967850.1
• Gene: Pum2 / 298874
• RGDID: 1311024
• Length: 1068
• Species: Rattus norvegicus
• Alignment Length: 1255
• Identity: 502/1255 - (40%)
• Similarity: 617/1255 - (49%)
• Gaps: 369/1255 - (29%)

  Fly   363 AVAAANRNAAITTSTAKKLWEKSDGKGVSSSTPGGPLHPLQIPGI--GDPSSVWKDHTWSTQGEN 425
            |:|..:|.......| ||.||..|      ||..|.      .||  ||..  |::..|.|...:
  Rat     7 ALALESRGMGELLPT-KKFWEPDD------STKDGQ------KGIFLGDDE--WRETAWGTSHHS 56

  Fly   426 ILVPPPSRAYAHGGASDTSNSGNAGILSPRDST---CAKVVEYVFSGSPTNKDSSLSGLEPHLRN 487
              :..|.......|.|...||....|||||..:   ...:||||.|.||.:|      |:...|.
  Rat    57 --MSQPIMVQRRSGQSFHGNSEVNAILSPRSESGGLGVSMVEYVLSSSPADK------LDSRFRK 113

  Fly   488 LKFDDNDKSRDDKEKAN-----SPFD---TNGLKKDDQVT--NSNGVVNGIDDD-KGFNRTPGSR 541
            ..|...|...|..||.:     |||:   ...||:||:.:  |..|:.||:|.| |.||||||||
  Rat   114 GTFGTRDAETDGPEKGDQKGKASPFEEDQNRDLKQDDEDSKINGRGLPNGMDADCKDFNRTPGSR 178

  Fly   542 QPSPAEESQPRPPNLLFPPLPFNHMLMDHGQGMGGGLGGVVGSGNGVGGGSGGGGAGGAYAAHQQ 606
            |.||.|..:...|: ..||           :|:|
  Rat   179 QASPTEVVERLGPS-TNPP-----------EGLG------------------------------- 200

  Fly   607 MAAQMSQLQPPMMNGVGGGMPMAAQSPML----NHQAAGPNHMESPGNLLQQQNFDVQQLFRSQN 667
                      |:.|       ..|..|::    |.:....:.|:..|  |....||.
  Rat   201 ----------PLPN-------PTANKPLVEEFSNPETQNLDAMDQVG--LDSLQFDY-------- 238

  Fly   668 PGLAAVATNAAAAAAAAAAATSAASAAAAVGAPPVPNGSLQQSQQQQQ----------QQQQQQQ 722
            ||                ......|:.|.||        |.....|||          ||....|
  Rat   239 PG----------------NQVPMDSSGATVG--------LFDYNSQQQLFQRTNALTVQQLTAAQ 279

  Fly   723 QQQMHMAAASQQFLAAQQQAQNAAYAAQQATSYVIN---PGQEAAPYMGMIAAAQM--------P 776
            |||..:|||.|..:|....| ..|.||.....|:|:   ||.:.....|:.|||.:        .
  Rat   280 QQQYALAAAQQPHIAGVFSA-GLAPAAFVPNPYIISAAPPGTDPYTAAGLAAAATLAGPAVVPPQ 343

  Fly   777 YYGVAPWGMYPGNLIPQQG---------------TQP-----------RRPLTPS--QQG----- 808
            |||| |||:||.||..||.               .||           :||:|||  |||
  Rat   344 YYGV-PWGVYPANLFQQQAAAAASNTANQQAASQAQPGQQQVLRPGAGQRPITPSQGQQGQQAES 407

  Fly   809 -----------------AENQP-YQVI--PAFLDHTGSLLMG-GPRT--GTPMRLVSPAPVLVPP 850
                             |...| |||:  .|:.|.||:|::| |.||  |.|:||::|.|||:..
  Rat   408 LAAAAAANPTLAFGQSLAAGMPGYQVLAPTAYYDQTGALVVGPGARTGLGAPVRLMAPTPVLISS 472

  Fly   851 GATRA--------------------------GPPPPQGPQLYQPQPQTAQQNLYSQQNGSSVGGL 889
            .|.:|                          |..|||  |..|.||.|   ||   |:.|..|..
  Rat   473 AAAQAAAAAAAAAGGTANSLTGSTNGLFRPIGTQPPQ--QQQQQQPST---NL---QSNSFYGSS 529

  Fly   890 ALNTSSLTGRRDSFDRSTSAFS-----PSTMDY---TSSGVAAAANAVNSTVAQAAAAAAAAAAA 946
            :|..||         :|:|.||     |.:...   :.|.:.||..:..|....:..::|:::|.
  Rat   530 SLTNSS---------QSSSLFSHGPGQPGSASLGFGSGSSLGAAIGSALSGFGSSVGSSASSSAT 585

  Fly   947 R-----------GKWPGAMSGAASGAYGALGAGNASASPLGAP---------ITPPP------SA 985
            |           .:...:::......|.:||. ::|.||:|.|         :||||      |:
  Rat   586 RRESLSTSSDLYKRSSSSLAPIGQPFYNSLGF-SSSPSPIGMPLPSQTPGHSLTPPPSLSSHGSS 649

  Fly   986 QSCLLG----------SRAPGAESRQRQQQQQQLAAVGLPATAAAAQAAVAAAANNMFGSNSSIF 1040
            .|..||          |.|||||::.|.                      |::.:::|.|:|.:|
  Rat   650 SSLHLGGLTNGSGRYISAAPGAEAKYRS----------------------ASSTSSLFSSSSQLF 692

  Fly  1041 SNPLAIPGTAAVAAAAAAAAAANSRQVAATAAAAAAVAAAAGGVGGAPQPGRSRLLEDFRNQRYP 1105
                           ..:....|...:..:                    |||||||||||.|:|
  Rat   693 ---------------PPSRLRYNRSDIMPS--------------------GRSRLLEDFRNNRFP 722

  Fly  1106 NLQLRDLANHIVEFSQDQHGSRFIQQKLERATAAEKQMVFSEILAAAYSLMTDVFGNYVIQKFFE 1170
            |||||||..|||||||||||||||||||||||.||:||||:||:.|||.||||||||||||||||
  Rat   723 NLQLRDLMGHIVEFSQDQHGSRFIQQKLERATPAERQMVFNEIVQAAYQLMTDVFGNYVIQKFFE 787

  Fly  1171 FGTPEQKNTLGMQVKGHVLQLALQMYGCRVIQKALESISPEQQ--QEIVHELDGHVLKCVKDQNG 1233
            ||:.:||..|..:::||||.|||||||||||||||||||.:||  .|:|.|||||||||||||||
  Rat   788 FGSLDQKLALANRIRGHVLPLALQMYGCRVIQKALESISSDQQVISEMVKELDGHVLKCVKDQNG 852

  Fly  1234 NHVVQKCIECVDPVALQFIINAFKGQVYSLSTHPYGCRVIQRILEHCTAEQTTPILDELHEHTEQ 1298
            |||||||||||.|.:|||||:||||||:.|||||||||||||||||||||||.|||:|||:||||
  Rat   853 NHVVQKCIECVQPQSLQFIIDAFKGQVFVLSTHPYGCRVIQRILEHCTAEQTLPILEELHQHTEQ 917

  Fly  1299 LIQDQYGNYVIQHVLEHGKQEDKSILINSVRGKVLVLSQHKFASNVVEKCVTHATRGERTGLIDE 1363
            |:||||||||||||||||:.||||.:::.:|||||.||||||||||||||||||:|.||..||||
  Rat   918 LVQDQYGNYVIQHVLEHGRPEDKSKIVSEIRGKVLALSQHKFASNVVEKCVTHASRAERALLIDE 982

  Fly  1364 VCTFND---NALHVMMKDQYANYVVQKMIDVSEPTQLKKLMTKIRPHMAALRKYTYGKHINAKLE 1425
            ||..||   :||:.||||||||||||||||::||.|.|.:|.|||||:..||||||||||.||||
  Rat   983 VCCQNDGPHSALYTMMKDQYANYVVQKMIDMAEPAQRKIIMHKIRPHITTLRKYTYGKHILAKLE 1047

  Fly  1426 KYYMKITNPITVGTGAGGVP 1445
            |||:|  |...:|. .||.|
  Rat  1048 KYYLK--NSPDLGP-IGGPP 1064

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pum	NP_001262403.1	Pumilio	1106..1424	CDD:153420	254/322 (79%)
Pum2	XP_038967850.1	Pumilio	723..1046	CDD:153420	254/322 (79%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342022
Domainoid	1	1.000	136	1.000	Domainoid score	I4804
eggNOG	1	0.900	-	-		E1_COG5099
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	649	1.000	Inparanoid score	I763
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000719
OrthoInspector	1	1.000	-	-		otm44506
orthoMCL	1	0.900	-	-		OOG6_100436
Panther	1	1.100	-	-	LDO	PTHR12537
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X849
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.840