Protein Alignment pum and puf4

DIOPT Version :10

• Sequence 1: NP_524285.2
• Gene: pum / 41094
• FlyBaseID: FBgn0003165
• Length: 1533
• Species: Drosophila melanogaster
• Sequence 2: NP_594123.1
• Gene: puf4 / 2542056
• PomBaseID: SPAC6G9.14
• Length: 681
• Species: Schizosaccharomyces pombe
• Alignment Length: 728
• Identity: 189/728 - (25%)
• Similarity: 317/728 - (43%)
• Gaps: 148/728 - (20%)

  Fly   760 GQEAAPYMGMIAAAQMPYYGVAPWGMYPGNLIPQQGTQPRRPLTPSQQGAEN-QPYQVI---PAF 820
            |.:||...|:.:.|         :|...||:  .:.|.    ::....|:.| .||.::   |:|
pombe    65 GSKAAVESGLASGA---------FGNRTGNM--NRNTS----MSGYTFGSSNFVPYNLLSNTPSF 114

  Fly   821 -LDHTGSLLMGGPRT--GTPMRLVSPAPVLVPPGA-------------------TRAGPPP---- 859
             ..|:.|.....|.|  |....|.||:..|..||:                   |.....|
pombe   115 TTSHSSSTTFVPPATMGGGLNNLSSPSSSLYLPGSASYQRSNSKNSSASILQMNTTLDDIPILLR 179

  Fly   860 PQGPQLYQPQPQTAQQNLYSQQN-GSSVGGLALNTSSLTGRRDSFDRSTSAFSPSTMDYTSSGVA 923
            ..|...|.|.|.|:::::.|..| |.:.|.:|.|.|:  .:..:|...:|:.:.||   |||  :
pombe   180 RPGLSSYTPGPSTSRRSISSSSNLGGNPGLIANNPSA--SKNFAFTSGSSSTNNST---TSS--S 237

  Fly   924 AAANAVNSTVAQAAA----AAAAAAAARGKWPG-AMSGAASGAYGALGAGNASASPLGAPITPPP 983
            :.||.:.|....:||    :.|.:.......|. |.|.|::|:..:.|:..|:......|...||
pombe   238 SMANGLQSISKHSAAFPLLSNATSFFGENLTPSLAASTASTGSTDSSGSNIANTLIAPTPTISPP 302

  Fly   984 SAQSCLLGSRAPGAESRQRQQQQQQLAAVGLPATAAAAQAAVAAAANNMFGSNSSIFSNPLAIPG 1048
            ||.:                        ||.|:.|                 ::..|:.|..|..
pombe   303 SANT------------------------VGNPSPA-----------------DTPGFNVPSLISD 326

  Fly  1049 TAAVAAAAAAAAAANSRQVAATAAAAAAVAAAAGGVGGAPQPGRSRLLEDFRNQRYPNLQLRDLA 1113
            ..:|:::.:::.|:.|.|                                              .
pombe   327 DPSVSSSLSSSVASLSLQ----------------------------------------------N 345

  Fly  1114 NHIVEFSQDQHGSRFIQQKLERATAAEKQMVFSEILAAAYSLMTDVFGNYVIQKFFEFGTPEQKN 1178
            ::|:.|.:||||.|::|:.||:...:....||:|.......||.|.||||:.||.||..:..|::
pombe   346 SNILSFCKDQHGCRYLQRLLEKKNQSHIDAVFAETHPYLAVLMVDAFGNYLCQKLFEHASEAQRS 410

  Fly  1179 TLGMQVKGHVLQLALQMYGCRVIQKALESI-SPEQQQEIVHELDGHVLKCVKDQNGNHVVQKCIE 1242
            |....:...::.::..|:|.|.:||.::.: ||:|...||:.|..:|:...||.|||||:|||:.
pombe   411 TFIQIIAPKLVPISFNMHGTRALQKIIDLVSSPDQISCIVNALRPNVVLLTKDLNGNHVIQKCLN 475

  Fly  1243 CVDPVALQFIINAFKGQVYSLSTHPYGCRVIQRILEHCTAEQTTPILDELHEHTEQLIQDQYGNY 1307
            .......|||.:|.......:|||.:||.|:||..:|.:..|...:::.:..|...|:||.:|||
pombe   476 KFSQEDCQFIFDAICEDPLDVSTHRHGCCVVQRCFDHASPAQIEQLVEHIVPHALTLVQDAFGNY 540

  Fly  1308 VIQHVLEHGKQEDKSILINSVRGKVLVLSQHKFASNVVEKCVTHATRGERTGLIDEVCTFNDNAL 1372
            |:|:|||.........:|:....||..||..||:|||:|||:..|....:..||.|:  .::..|
pombe   541 VLQYVLELNNPNHTEAIISYFLYKVRALSTQKFSSNVMEKCIFFAPAAIKEKLISEL--MDEKHL 603

  Fly  1373 HVMMKDQYANYVVQKMIDVSEPTQLKKLMTKIRPHMAALRKYTYGKHINAKLEKYYMKITNPITV 1437
            ..:::|.:||||:|..:|.:...|..:|:.:|:|.:.:::....|:.|.:|||:.:........|
pombe   604 PKLLRDSFANYVIQTALDNASVKQRAELVERIKPLIPSIKNTPCGRRILSKLERRHPSSKEKPIV 668

  Fly  1438 GTGAGGVPAASSA 1450
            .:.:..|..:|||
pombe   669 YSNSERVNTSSSA 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pum	NP_524285.2	Pumilio	1106..1424	CDD:153420	105/318 (33%)
puf4	NP_594123.1	COG5099	1..678	CDD:227430	186/723 (26%)