DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment pum and SPAC6G9.14

DIOPT Version :9

Sequence 1:	NP_001262403.1	Gene:	pum / 41094	FlyBaseID:	FBgn0003165	Length:	1533	Species:	Drosophila melanogaster
Sequence 2:	NP_594123.1	Gene:	SPAC6G9.14 / 2542056	PomBaseID:	SPAC6G9.14	Length:	681	Species:	Schizosaccharomyces pombe

Alignment Length:	728	Identity:	189/728 - (25%)
Similarity:	317/728 - (43%)	Gaps:	148/728 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   760 GQEAAPYMGMIAAAQMPYYGVAPWGMYPGNLIPQQGTQPRRPLTPSQQGAEN-QPYQVI---PAF 820
            |.:||...|:.:.|         :|...||:  .:.|.    ::....|:.| .||.::   |:|
pombe    65 GSKAAVESGLASGA---------FGNRTGNM--NRNTS----MSGYTFGSSNFVPYNLLSNTPSF 114

  Fly   821 -LDHTGSLLMGGPRT--GTPMRLVSPAPVLVPPGA-------------------TRAGPPP---- 859
             ..|:.|.....|.|  |....|.||:..|..||:                   |.....|
pombe   115 TTSHSSSTTFVPPATMGGGLNNLSSPSSSLYLPGSASYQRSNSKNSSASILQMNTTLDDIPILLR 179

  Fly   860 PQGPQLYQPQPQTAQQNLYSQQN-GSSVGGLALNTSSLTGRRDSFDRSTSAFSPSTMDYTSSGVA 923
            ..|...|.|.|.|:::::.|..| |.:.|.:|.|.|:  .:..:|...:|:.:.||   |||  :
pombe   180 RPGLSSYTPGPSTSRRSISSSSNLGGNPGLIANNPSA--SKNFAFTSGSSSTNNST---TSS--S 237

  Fly   924 AAANAVNSTVAQAAA----AAAAAAAARGKWPG-AMSGAASGAYGALGAGNASASPLGAPITPPP 983
            :.||.:.|....:||    :.|.:.......|. |.|.|::|:..:.|:..|:......|...||
pombe   238 SMANGLQSISKHSAAFPLLSNATSFFGENLTPSLAASTASTGSTDSSGSNIANTLIAPTPTISPP 302

  Fly   984 SAQSCLLGSRAPGAESRQRQQQQQQLAAVGLPATAAAAQAAVAAAANNMFGSNSSIFSNPLAIPG 1048
            ||.:                        ||.|:.|                 ::..|:.|..|..
pombe   303 SANT------------------------VGNPSPA-----------------DTPGFNVPSLISD 326

  Fly  1049 TAAVAAAAAAAAAANSRQVAATAAAAAAVAAAAGGVGGAPQPGRSRLLEDFRNQRYPNLQLRDLA 1113
            ..:|:::.:::.|:.|.|                                              .
pombe   327 DPSVSSSLSSSVASLSLQ----------------------------------------------N 345

  Fly  1114 NHIVEFSQDQHGSRFIQQKLERATAAEKQMVFSEILAAAYSLMTDVFGNYVIQKFFEFGTPEQKN 1178
            ::|:.|.:||||.|::|:.||:...:....||:|.......||.|.||||:.||.||..:..|::
pombe   346 SNILSFCKDQHGCRYLQRLLEKKNQSHIDAVFAETHPYLAVLMVDAFGNYLCQKLFEHASEAQRS 410

  Fly  1179 TLGMQVKGHVLQLALQMYGCRVIQKALESI-SPEQQQEIVHELDGHVLKCVKDQNGNHVVQKCIE 1242
            |....:...::.::..|:|.|.:||.::.: ||:|...||:.|..:|:...||.|||||:|||:.
pombe   411 TFIQIIAPKLVPISFNMHGTRALQKIIDLVSSPDQISCIVNALRPNVVLLTKDLNGNHVIQKCLN 475

  Fly  1243 CVDPVALQFIINAFKGQVYSLSTHPYGCRVIQRILEHCTAEQTTPILDELHEHTEQLIQDQYGNY 1307
            .......|||.:|.......:|||.:||.|:||..:|.:..|...:::.:..|...|:||.:|||
pombe   476 KFSQEDCQFIFDAICEDPLDVSTHRHGCCVVQRCFDHASPAQIEQLVEHIVPHALTLVQDAFGNY 540

  Fly  1308 VIQHVLEHGKQEDKSILINSVRGKVLVLSQHKFASNVVEKCVTHATRGERTGLIDEVCTFNDNAL 1372
            |:|:|||.........:|:....||..||..||:|||:|||:..|....:..||.|:  .::..|
pombe   541 VLQYVLELNNPNHTEAIISYFLYKVRALSTQKFSSNVMEKCIFFAPAAIKEKLISEL--MDEKHL 603

  Fly  1373 HVMMKDQYANYVVQKMIDVSEPTQLKKLMTKIRPHMAALRKYTYGKHINAKLEKYYMKITNPITV 1437
            ..:::|.:||||:|..:|.:...|..:|:.:|:|.:.:::....|:.|.:|||:.:........|
pombe   604 PKLLRDSFANYVIQTALDNASVKQRAELVERIKPLIPSIKNTPCGRRILSKLERRHPSSKEKPIV 668

  Fly  1438 GTGAGGVPAASSA 1450
            .:.:..|..:|||
pombe   669 YSNSERVNTSSSA 681

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pum	NP_001262403.1	Pumilio	1106..1424	CDD:153420	105/318 (33%)
SPAC6G9.14	NP_594123.1	COG5099	1..678	CDD:227430	186/723 (26%)
SPAC6G9.14	NP_594123.1	Pumilio	344..655	CDD:153420	106/358 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5099
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000719
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.770