Protein Alignment pum and puf-9

DIOPT Version :10

• Sequence 1: NP_524285.2
• Gene: pum / 41094
• FlyBaseID: FBgn0003165
• Length: 1533
• Species: Drosophila melanogaster
• Sequence 2: NP_508980.2
• Gene: puf-9 / 180850
• WormBaseID: WBGene00004245
• Length: 703
• Species: Caenorhabditis elegans
• Alignment Length: 697
• Identity: 263/697 - (37%)
• Similarity: 341/697 - (48%)
• Gaps: 140/697 - (20%)

  Fly   789 NLI--PQQGTQPRRPLTPSQQGAENQPYQVIPAFLDHTGSLLMGGPRTGTPMRLVSPAPVLVPPG 851
            ||:  |....|.|...|.:       |:.:..:..|.....:||....|.|:    |.|   ..|
 Worm    58 NLVGSPSSSVQQRNYFTTT-------PFPISRSPNDRNDDKIMGNGSYGVPI----PIP---QDG 108

  Fly   852 ATRAGPPPPQGPQLYQPQPQTAQQNLYSQQNGSSVGGLALNTSSLTGRRDSFDRSTSAFSPSTMD 916
            .       |||...:|..|       :.||.|..:||.......::|  :.:......||.....
 Worm   109 V-------PQGTPDFQMTP-------FLQQGGHLIGGSPNGPVQVSG--NWYSGGAGIFSTMQQA 157

  Fly   917 YTSSGVAAAA----NAVNSTVAQAAAAAAAAAAARGKWPGAMSGAASGAYGALGAGNASASPLGA 977
            ..|:|:...|    |..|...........|..:....:|.......:.::||:|.|.........
 Worm   158 DPSNGMPGMAAEFVNNENGMPGPNGMHQQAMISGSPPFPYQNMMNLTTSFGAMGLGPQQIQQRDP 222

  Fly   978 PITPPPSAQSCLLGSRAPGAESR--------------QRQQQQQQLAAVGLPATAAAAQAAVAAA 1028
            .:...|.....:.|....|...:              |.|||.|||          |.|......
 Worm   223 QMFQQPILHEPIQGMAQNGFGQQVFFTQMQNQQHPQGQAQQQLQQL----------AQQHQQQQN 277

  Fly  1029 ANNMFGSNSSIFSNPLAIPGTAAVAAAAAAAAAANSRQVAATAAAAAAVAAAAGGV--------G 1085
            :...||...:...|                                       |||        .
 Worm   278 SQQFFGQGPNGMGN---------------------------------------GGVMNDWSQRSF 303

  Fly  1086 GAPQ---------------PGRSRLLEDFRNQRYPNLQ----LRDLANHIVEFSQDQHGSRFIQQ 1131
            |.||               |.|.|..||      ||.|    |:|:.|:::||::||||||||||
 Worm   304 GMPQQQAQQNGLPPNFSQNPPRRRGPED------PNGQTPKTLQDIKNNVIEFAKDQHGSRFIQQ 362

  Fly  1132 KLERATAAEKQMVFSEILAAAYSLMTDVFGNYVIQKFFEFGTPEQKNTLGMQVKGHVLQLALQMY 1196
            |||||:..:|..:|:.:|..|..||||||||||||||||||..||:|.|...::|:|::||||||
 Worm   363 KLERASLRDKAAIFTPVLENAEELMTDVFGNYVIQKFFEFGNNEQRNQLVGTIRGNVMKLALQMY 427

  Fly  1197 GCRVIQKALESISPEQQQEIVHELDGHVLKCVKDQNGNHVVQKCIECVDPVALQFIINAF----K 1257
            ||||||||||.:..:.|.||:.|::|.|||||||||||||:||.||.|:|..|||||:||    .
 Worm   428 GCRVIQKALEYVEEKYQHEILGEMEGQVLKCVKDQNGNHVIQKVIERVEPERLQFIIDAFTKNNS 492

  Fly  1258 GQVYSLSTHPYGCRVIQRILEHCTAEQTTPILDELHEHTEQLIQDQYGNYVIQHVLEHGKQEDKS 1322
            ..||:||.||||||||||:||:|..||..|:||.|..|.:||:.|||||||||||:|||...||.
 Worm   493 DNVYTLSVHPYGCRVIQRVLEYCNEEQKQPVLDALQIHLKQLVLDQYGNYVIQHVIEHGSPSDKE 557

  Fly  1323 ILINSV-RGKVLVLSQHKFASNVVEKCVTHATRGERTGLIDEVC-TFNDNA--LHVMMKDQYANY 1383
            .::..| ...:|..:||||||||:|||:|.....||..:||:|| ..||.:  |..||||.:|||
 Worm   558 QIVQDVISDDLLKFAQHKFASNVIEKCLTFGGHAERNLIIDKVCGDPNDPSPPLLQMMKDPFANY 622

  Fly  1384 VVQKMIDVSEPTQLKKLMTKIRPHMAALRKYTYGKHINAKLEKYYMK 1430
            |||||:||::|...||:...|:||:|.||||.:||||..|||||:.|
 Worm   623 VVQKMLDVADPQHRKKITLTIKPHIATLRKYNFGKHILLKLEKYFAK 669

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pum	NP_524285.2	Pumilio	1106..1424	CDD:153420	191/329 (58%)
puf-9	NP_508980.2	Med15	28..>324	CDD:312941	60/344 (17%)
		Pumilio	339..663	CDD:153420	189/323 (59%)