Protein Alignment pum and puf-5

DIOPT Version :10

• Sequence 1: NP_524285.2
• Gene: pum / 41094
• FlyBaseID: FBgn0003165
• Length: 1533
• Species: Drosophila melanogaster
• Sequence 2: NP_495814.1
• Gene: puf-5 / 174373
• WormBaseID: WBGene00004241
• Length: 553
• Species: Caenorhabditis elegans
• Alignment Length: 575
• Identity: 122/575 - (21%)
• Similarity: 223/575 - (38%)
• Gaps: 136/575 - (23%)

  Fly   929 VNSTVAQAAAAAAAAAAARGKWPGAMSGAASGA-----YGALGAGNASASPLGAPITPPPSAQS- 987
            :||..:.:::.:....|....:.|:..|.|..:     :..:|.||....     .:|.|.|:|
 Worm     8 INSKASDSSSISDHQTADLSIFNGSFDGGAFSSSNIPLFNFMGTGNQRFQ-----YSPHPFAKSS 67

  Fly   988 --CLLGSRAPGAESRQRQQQQQQLAAVGLPATAAAAQAAVAAAANNMF----GSNSSIFSNPLAI 1046
              |.|.:..|......            |..|.|....|..:..|..|    .:|:|...|..:.
 Worm    68 DPCRLAALTPSTPKGP------------LNLTPADFGLADFSVGNESFADFTANNTSFVGNVQSN 120

  Fly  1047 PGTAAVAAAAAAAAAANSRQVAATAAAAAAVAAAAGGVGGAPQPGRSRLLEDFRNQRYPNLQLRD 1111
            ..:..:..|.|...:.|.|.                                       :|.|:|
 Worm   121 VRSTRLLPAWAVDNSGNIRD---------------------------------------DLTLQD 146

  Fly  1112 LANH--IVEFSQDQHGSRFIQQKLERATAAEKQMVFSEIL----AAAYSLMTDVFGNYVIQKFFE 1170
            :.::  :::|:.|:.|.:|:::........|...|..:.|    |...||.....||::||||.|
 Worm   147 VVSNGSLIDFAMDRTGVKFLERHFPEDHDNEMHFVLFDKLTEQGAVFTSLCRSAAGNFIIQKFVE 211

  Fly  1171 FGT-PEQKNTLGMQVKGHVLQLALQMYGCRVIQKALESISPEQQQEIVHELDG-HVLKCVKDQNG 1233
            ..| .||:..:.......::::.|..:.|||:|.:::........::|.::.. ..|....||..
 Worm   212 HATLDEQERLVRKMCDNGLIEMCLDKFACRVVQMSIQKFDVSIAMKLVEKISSLDFLPLCTDQCA 276

  Fly  1234 NHVVQKCIECVDPVALQFIINAF--KGQVYSLSTHPYGCRVIQRILE--------HCTAEQTTPI 1288
            .||:||.::.:...|..|.:...  ...:.::....||||::|:.::        ||...:
 Worm   277 IHVLQKVVKLLPISAWSFFVKFLCRDDNLMTVCQDKYGCRLVQQTIDKLSDNPKLHCFNTR---- 337

  Fly  1289 LDELH-------EHTEQLIQDQYGNYVIQHVLE-HGKQE-------DKSILINSVRGKVLVLSQH 1338
            |..||       .:..:|..:::.|||:|:|:: .|..|       :|.:|.|     :|.:||.
 Worm   338 LQLLHGLMTSVARNCFRLSSNEFANYVVQYVIKSSGVMEMYRDTIIEKCLLRN-----ILSMSQD 397

  Fly  1339 KFASNVVEKCVTHATRGERTGLIDEVC-------TFNDNALHVMMKDQYANYVVQKMIDVSEPTQ 1396
            |:||:|||.....|.....:.::||:.       ..|.:||.:::..||.|||||:||.:.....
 Worm   398 KYASHVVEGAFLFAPPLLLSEMMDEIFDGYVKDQETNRDALDILLFHQYGNYVVQQMISICISAL 462

  Fly  1397 LKK-------------------LMTKIRPHMAALRKYTYGKHINAKLEKYYMKIT 1432
            |.|                   :..::..|...|.:::.||.|...|:|..:.:|
 Worm   463 LGKEERKMVASEMRLYAKWFDRIKNRVNRHSGRLERFSSGKKIIESLQKLNVPMT 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pum	NP_524285.2	Pumilio	1106..1424	CDD:153420	90/376 (24%)
puf-5	NP_495814.1	Pumilio	142..509	CDD:480718	90/375 (24%)