Protein Alignment pum and pum2

DIOPT Version :10

• Sequence 1: NP_524285.2
• Gene: pum / 41094
• FlyBaseID: FBgn0003165
• Length: 1533
• Species: Drosophila melanogaster
• Sequence 2: XP_002934529.2
• Gene: pum2 / 100496617
• XenbaseID: XB-GENE-977105
• Length: 1181
• Species: Xenopus tropicalis
• Alignment Length: 1359
• Identity: 519/1359 - (38%)
• Similarity: 644/1359 - (47%)
• Gaps: 425/1359 - (31%)

  Fly   286 HAAA--------LGHMSSYAQSGGSMYDHHGGAMHPGMNGGMPKQQPLGPPGAGGPQDYVYMGGQ 342
            ||::        :|.:.|.|.|.|..:.::..||.|   |....|.||    :|..||...:|..
 Frog    22 HASSGQEALGVGVGMVPSGAASAGQAHGNNPNAMPP---GAASAQVPL----SGRSQDDATVGYF 79

  Fly   343 TTVPMGAAMMPPQNQYMN------SSAVAAANRNA--------AITTST--------AKKLWEKS 385
            .....|..:    |.|.|      ..::.||.|:.        |:...:        |||.||..
 Frog    80 FQRQAGEQL----NGYANKHRWPTGDSIDAAVRSVDEMNHDFQALALESRGMGELLPAKKFWEHE 140

  Fly   386 D-----GKGVSSSTPGGPLHPLQIPGIGDPSSVWKDHTWSTQGENILVP-----PPSRAYAHGGA 440
            |     .||:.               :.|.   |:::||.....::..|     .|.::: ||
 Frog   141 DPAKDGQKGMF---------------LADE---WRENTWGASHHSMSQPIMVQRRPGQSF-HG-- 184

  Fly   441 SDTSNSGNAGILSPRDST---CAKVVEYVFSGSPTNKDSSLSGLEPHLRNLKFDDNDKSRDDKEK 502
                |...|.:||||..:   ...:||||.|.||.:|      |:|..|...|...|...|..||
 Frog   185 ----NHDVASVLSPRSESGGLGVSMVEYVLSSSPADK------LDPRFRKGVFSVRDCELDGPEK 239

  Fly   503 AN-----SPFDTNGLKKDDQVT---------NSNGVVNGIDDD-KGFNRTPGSRQPSPAEESQPR 552
            ..     |||:..  ||.|.::         |..|:.||||.| |.|||||||||.||.|..:..
 Frog   240 GEQKGKASPFEEE--KKRDLISADPDDVSKLNGRGLPNGIDTDCKDFNRTPGSRQASPTEIIERI 302

  Fly   553 PPNLLFPPLPFNHMLMDHGQGMGGGLGGVVGSGNGVGGGSGGGGAGGAYAAHQQMAAQMSQLQPP 617
            .||                                                 ...|..:.|.|..
 Frog   303 GPN-------------------------------------------------SSSAEVLGQHQNH 318

  Fly   618 MMNGVGGGMPMAAQSPMLNHQ------AAGPNHM--ESPGNLLQQQN-------FDV---QQLFR 664
            |.|     .|::.:.|....|      ..|.:.:  :.|||.:|..:       ||.   ||||:
 Frog   319 MNN-----KPLSDEFPSTESQNLDGMEQVGLDSLQFDYPGNQIQMDSAGAGVSLFDYNTQQQLFQ 378

  Fly   665 SQNPGLAAVATNAAAAAAAAAAATSAASAAAAVGAPPVPNGSLQQSQQQQQQQQQQQQQQQMHMA 729
            .||                                          :...||....||||||..:|
 Frog   379 RQN------------------------------------------TLTVQQLTAAQQQQQQFTLA 401

  Fly   730 AASQQFLAAQQQAQNAAYAAQQATSYVINPGQEAA-PY--MGMIAAAQM--------PYYGVAPW 783
            ||.||.|.....| ..|.||.....|:|:.|...| ||  .|:.|||.:        .|||| ||
 Frog   402 AAQQQHLTGMFSA-GLAPAAFVPNPYIISAGHPGADPYTAAGLAAAATLAGPAVVPPQYYGV-PW 464

  Fly   784 GMYPGNLIPQQ----------------------------GTQPRRPLTPS--QQG---------A 809
            |:||..|..||                            .|..:|||||:  |||         |
 Frog   465 GVYPAGLFQQQAAAAATAASSNNQQAATQATQGQQQVMRATSSQRPLTPNQGQQGQQPESLAAAA 529

  Fly   810 ENQP-------------YQVI--PAFLDHTGSLLMG-GPRTG--TPMRLVSPAPVLVPPGATRAG 856
            .||.             |||:  .|:.|.||:|::| |.|.|  ..:|||:..|||:.|.|.:|.
 Frog   530 ANQAQIFGQGLATSMPGYQVLTPTAYYDQTGALVVGPGARAGLAAQVRLVASGPVLISPAAAQAA 594

  Fly   857 --------------------PPPPQGPQLYQPQPQTAQQNLYSQQNGSSVGGLALNTSSLTGRRD 901
                                |..||..|..|||.|....||:|   .|..|..|:..:|
 Frog   595 AAASATGANSLTGPTNSIFRPLGPQQQQQQQPQQQQPNANLHS---SSFYGNSAMTNNS------ 650

  Fly   902 SFDRSTSAFS--PSTMDYTSSGVAAAANAVNSTVAQA----AAAAAAAAAARGKWPGAMSGAA-- 958
               :|:|.||  |.....||.|. .::|::.|.:..|    .::...:|.:.|....::|.::
 Frog   651 ---QSSSLFSHGPGQPGNTSLGF-GSSNSLGSAIGSAFGGFGSSVGNSAGSSGSRRDSLSASSDL 711

  Fly   959 ------------SGAYGALGAGNASASPLGAP---------ITPPP------SAQSCLLG----- 991
                        ...|.:||. ::|.||:|.|         :||||      |:.|..||
 Frog   712 YKRSSSSLAPIGQPFYNSLGF-SSSPSPIGMPLPSQTSGHSLTPPPSLSSHGSSSSLHLGGLTNG 775

  Fly   992 -----SRAPGAESRQRQQQQQQLAAVGLPATAAAAQAAVAAAANNMFGSNSSIFSNPLAIPGTAA 1051
                 |.|||||::.|.                      ||:.::.|.|||.:|
 Frog   776 SGRYISAAPGAEAKYRS----------------------AASTSSFFSSNSQLF----------- 807

  Fly  1052 VAAAAAAAAAANSRQVAATAAAAAAVAAAAGGVGGAPQPGRSRLLEDFRNQRYPNLQLRDLANHI 1116
                ..:....|...:..:                    |||||||||||.|:||||||||..||
 Frog   808 ----PPSRLRYNRADIMPS--------------------GRSRLLEDFRNNRFPNLQLRDLMGHI 848

  Fly  1117 VEFSQDQHGSRFIQQKLERATAAEKQMVFSEILAAAYSLMTDVFGNYVIQKFFEFGTPEQKNTLG 1181
            ||||||||||||||||||||:.||:|:||||||.|||.||||||||||||||||||:.:||..|.
 Frog   849 VEFSQDQHGSRFIQQKLERASPAERQLVFSEILQAAYQLMTDVFGNYVIQKFFEFGSMDQKLALA 913

  Fly  1182 MQVKGHVLQLALQMYGCRVIQKALESISPEQQQEIVHELDGHVLKCVKDQNGNHVVQKCIECVDP 1246
            .:::||||.|||||||||||||||||||.:||.|:|.||||||||||||||||||||||||||.|
 Frog   914 TRIRGHVLPLALQMYGCRVIQKALESISIDQQSEMVRELDGHVLKCVKDQNGNHVVQKCIECVQP 978

  Fly  1247 VALQFIINAFKGQVYSLSTHPYGCRVIQRILEHCTAEQTTPILDELHEHTEQLIQDQYGNYVIQH 1311
            .:|||||:|||||||.|||||||||||||||||||.|||.|||:|||:.||||:|||||||||||
 Frog   979 QSLQFIIDAFKGQVYVLSTHPYGCRVIQRILEHCTPEQTLPILEELHQSTEQLVQDQYGNYVIQH 1043

  Fly  1312 VLEHGKQEDKSILINSVRGKVLVLSQHKFASNVVEKCVTHATRGERTGLIDEVCTFNDN---ALH 1373
            |||||:.:|||.:::.||||||.|||||||||||||||||::|.||..||||:|..||.   ||:
 Frog  1044 VLEHGRSDDKSKIVSEVRGKVLALSQHKFASNVVEKCVTHSSRTERALLIDEICCQNDGPHCALY 1108

  Fly  1374 VMMKDQYANYVVQKMIDVSEPTQLKKLMTKIRPHMAALRKYTYGKHINAKLEKYYMKIT 1432
            .||||||||||||||||::||.|.|.:|.|||||:..||||||||||.|||||||||.|
 Frog  1109 TMMKDQYANYVVQKMIDMAEPAQRKIIMHKIRPHITTLRKYTYGKHILAKLEKYYMKNT 1167

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pum	NP_524285.2	Pumilio	1106..1424	CDD:153420	251/320 (78%)
pum2	XP_002934529.2	dermokine	<637..>718	CDD:455732	19/93 (20%)
		Pumilio	838..1159	CDD:153420	251/320 (78%)