Protein Alignment Ada and AMD1

DIOPT Version :9

• Sequence 1: NP_649866.1
• Gene: Ada / 41092
• FlyBaseID: FBgn0037661
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: NP_013677.1
• Gene: AMD1 / 854973
• SGDID: S000004498
• Length: 810
• Species: Saccharomyces cerevisiae
• Alignment Length: 414
• Identity: 82/414 - (19%)
• Similarity: 130/414 - (31%)
• Gaps: 132/414 - (31%)

  Fly    10 KVELHAHLNGSLGIKSLCDLGERLYGTSCKDFLKLCAHFSRFEKDMDACF---------EKFAFV 65
            ||:.|.|.:..:..|.|               |:...|..|..||....|         |.|..:
Yeast   358 KVDTHVHHSACMNQKHL---------------LRFIKHKLRHSKDEKVIFRDGKLLTLDEVFRSL 407

  Fly    66 HELTSTREGLRFATELAIRD----FAEDNVQY-----VEMRTTPKANENYSRRDYL-----QIVI 116
            | ||.....:......|.:|    |.:.|::|     ..:|.......||.:..||     |::.
Yeast   408 H-LTGYDLSIDTLDMHAHKDTFHRFDKFNLKYNPIGESRLREIFLKTNNYIKGTYLADITKQVIF 471

  Fly   117 D-----------AIKAASETYPE---------------ITVKLLPSINRAEPV-----------D 144
            |           .|.....:..|               ..|:.|..|.|...:           |
Yeast   472 DLENSKYQNCEYRISVYGRSLDEWDKLASWVIDNKVISHNVRWLVQIPRLYDIYKKTGIVQSFQD 536

  Fly   145 VAEETVSLAVELAR---AHPNL------ILGIDLSGNPGK--GRF-------------------- 178
            :.:.......|:.:   :||.|      ::|.|...:..|  .||
Yeast   537 ICKNLFQPLFEVTKNPQSHPKLHVFLQRVIGFDSVDDESKVDRRFHRKYPKPSLWEAPQNPPYSY 601

  Fly   179 ------SDFAPILAQARDKG---LKLAIHCAEIENPSEVKE--MLHFGMSRCGHGTFLTPEDIGQ 232
                  |:.|.:......:|   |.|..||.|..:|..:..  :|..|:|   ||..|......|
Yeast   602 YLYYLYSNVASLNQWRAKRGFNTLVLRPHCGEAGDPEHLVSAYLLAHGIS---HGILLRKVPFVQ 663

  Fly   233 ----LKQRNIAIECCLTSNVKSGTVPSLEEHHLKRIMEADAPKVICTDDSGVFDTT---LTKEFL 290
                |.|..||:. .|::|....|   .:::...|..:......:.|||...|..|   |.:|:.
Yeast   664 YLYYLDQVGIAMS-PLSNNALFLT---YDKNPFPRYFKRGLNVSLSTDDPLQFSYTREPLIEEYS 724

  Fly   291 IAAETFGLTREQCIDLTLEAVHHS 314
            :||:.:.|:.....:|...:|..|
Yeast   725 VAAQIYKLSNVDMCELARNSVLQS 748

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ada	NP_649866.1	ADA_AMPD	8..327	CDD:238250	82/414 (20%)
AMD1	NP_013677.1	AMPD	299..794	CDD:238644	82/414 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900