DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ada and Adal

DIOPT Version :9

Sequence 1:	NP_649866.1	Gene:	Ada / 41092	FlyBaseID:	FBgn0037661	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	XP_008760388.1	Gene:	Adal / 311352	RGDID:	1359517	Length:	360	Species:	Rattus norvegicus

Alignment Length:	338	Identity:	135/338 - (39%)
Similarity:	203/338 - (60%)	Gaps:	21/338 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 FLKGLPKVELHAHLNGSLGIKSLCDLGERLYGTSCKDFLKLCAHFSRFEK----DMDACFEKFAF 64
            |...|||||||||||||:...::..|      .:.|..|::..|.:..:|    .::.||:.|..
  Rat    13 FYMQLPKVELHAHLNGSISSSTMRKL------IAKKPHLQVHGHMTMIDKGKKRTLEECFQMFQV 71

  Fly    65 VHELTSTREGLRFATELAIRDFAEDNVQYVEMRTTPKANEN---YSRRDYLQIVIDAIKAASETY 126
            :|:||::.|.:...|:..|::||:|.|:|:|:|:||: .||   .:|:.|::.|::.||...:..
  Rat    72 IHQLTTSAEDILMVTKDVIKEFADDGVKYLELRSTPR-GENATGMTRKTYVESVLEGIKQCKQEN 135

  Fly   127 PEITVKLLPSINRAEPVDVAEETVSLAVELARAHPNLILGIDLSGNPGKGRFSDFAPILAQARDK 191
            .:|.|:.|.:|:|.....||:|||.||.|...:..:.:||:||||:|..|:..||...|.:|:..
  Rat   136 LDIDVRYLMAIDRKGGPTVAKETVKLAKEFFLSAEDTVLGLDLSGDPTIGQAKDFLEPLLEAKKA 200

  Fly   192 GLKLAIHCAEIEN-PSEVKEMLHFGMSRCGHGTFL-TPE-----DIGQLKQRNIAIECCLTSNVK 249
            |||||:|.|||.| ..|.:.:|.....|.|||||| |||     .:..::|..|.:|.|||||:|
  Rat   201 GLKLALHLAEIPNKEKETQMLLDLLPDRIGHGTFLNTPEAGSVDQVNFVRQHRIPLELCLTSNIK 265

  Fly   250 SGTVPSLEEHHLKRIMEADAPKVICTDDSGVFDTTLTKEFLIAAETFGLTREQCIDLTLEAVHHS 314
            |.||||.::||.........|.||||||.|||.|:|::|:.:|||||.||..|..||:.|::::.
  Rat   266 SQTVPSYDQHHFGFWYSVAHPSVICTDDKGVFATSLSQEYQLAAETFNLTPSQVWDLSYESINYI 330

  Fly   315 FASEQEQIQMADR 327
            |||...:.::..|
  Rat   331 FASNNTRSELRKR 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ada	NP_649866.1	ADA_AMPD	8..327	CDD:238250	133/332 (40%)
Adal	XP_008760388.1	ADA_AMPD	17..344	CDD:238250	134/334 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353073
Domainoid	1	1.000	151	1.000	Domainoid score	I4270
eggNOG	1	0.900	-	-		E1_COG1816
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	153	1.000	Inparanoid score	I4258
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D511781at33208
OrthoFinder	1	1.000	-	-		FOG0006051
OrthoInspector	1	1.000	-	-		oto98455
orthoMCL	1	0.900	-	-		OOG6_103864
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4344
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.660