DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ada and AMPD2

DIOPT Version :10

Sequence 1:NP_649866.1 Gene:Ada / 41092 FlyBaseID:FBgn0037661 Length:337 Species:Drosophila melanogaster
Sequence 2:NP_004028.4 Gene:AMPD2 / 271 HGNCID:469 Length:825 Species:Homo sapiens


Alignment Length:150 Identity:35/150 - (23%)
Similarity:55/150 - (36%) Gaps:27/150 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   178 FSDFAPILAQARDKGLK---LAIHCAEIENPSEVKEMLHFGMS------RCGHGTFLTPEDIGQ- 232
            |::.|.:....|.:|..   |..||.| ..|      :|..:|      ...||..|....:.| 
Human   610 FANMAMLNHLRRQRGFHTFVLRPHCGE-AGP------IHHLVSAFMLAENISHGLLLRKAPVLQY 667

  Fly   233 ---LKQRNIAIECCLTSNVKSGTVPSLEEHHLKRIMEADAPKVICTDDSGVFDTT---LTKEFLI 291
               |.|..||:. .|::|   ....|...:.|...:.......:.|||...|..|   |.:|:.|
Human   668 LYYLAQIGIAMS-PLSNN---SLFLSYHRNPLPEYLSRGLMVSLSTDDPLQFHFTKEPLMEEYSI 728

  Fly   292 AAETFGLTREQCIDLTLEAV 311
            |.:.:.|:.....:|...:|
Human   729 ATQVWKLSSCDMCELARNSV 748

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AdaNP_649866.1 ADA_AMPD 8..327 CDD:238250 34/149 (23%)
AMPD2NP_004028.4 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..49
AMP_deaminase 163..806 CDD:437158 34/149 (23%)
Blue background indicates that the domain is not in the aligned region.

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